• Western blot analysis using ACE1 monoclonal antibody against mouse kidney lysate.

Anti-ACE antibody (N-Term) (STJ98458)

SKU:
STJ98458

Current Stock:
Host: Mouse
Applications: WB
Reactivity: Human, Mouse, Rat, Bovine
Note: FOR RESEARCH USE ONLY (RUO).
Short Description: Mouse monoclonal antibody anti-Angiotensin-Converting Enzyme (N-Term) is suitable for use in Western Blot research applications.
Clonality: Monoclonal
Conjugation: Unconjugated
Formulation: Buffer, 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% Sodium Azide, 50% Glycerol.
Purification: The antibody was isolated from ascitic fluid by immunoaffinity chromatography using antigens coupled to agarose beads.
Concentration: 1 mg/mL
Dilution Range: WB 1:1000-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: ACE
Gene ID: 1636
Uniprot ID: ACE_HUMAN
Immunogen Region: N-Term
Specificity: ACE monoclonal antibody (Angiotensin-Converting Enzyme) binds to endogenous Angiotensin-Converting Enzyme at the amino acid region N-Term.
Immunogen: Purified recombinant human ACE1 (N-terminus) protein fragments expressed in E.coli.
Post Translational Modifications Phosphorylated by CK2 on Ser-1299.which allows membrane retention.
Function Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilator. Has also a glycosidase activity which releases GPI-anchored proteins from the membrane by cleaving the mannose linkage in the GPI moiety.
Protein Name Angiotensin-Converting Enzyme
Ace
Dipeptidyl Carboxypeptidase I
Kininase Ii
Cd Antigen Cd143 Cleaved Into - Angiotensin-Converting Enzyme - Soluble Form
Database Links Reactome: R-HSA-2022377
Cellular Localisation Angiotensin-Converting Enzyme
Soluble Form: Secreted
Cell Membrane
Single-Pass Type I Membrane Protein
Cytoplasm
Detected In Both Cell Membrane And Cytoplasm In Neurons
Alternative Antibody Names Anti-Angiotensin-Converting Enzyme antibody
Anti-Ace antibody
Anti-Dipeptidyl Carboxypeptidase I antibody
Anti-Kininase Ii antibody
Anti-Cd Antigen Cd143 Cleaved Into - Angiotensin-Converting Enzyme - Soluble Form antibody
Anti-ACE antibody
Anti-DCP antibody
Anti-DCP1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance