Anti-ACADSB antibody (STJA0007415)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human ACADSB
General Information
| Short Description | Rabbit polyclonal anti-Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ACADSB |
| Gene ID | 36 |
| Uniprot ID | ACDSB_HUMAN |
| Immunogen | Synthesized peptide derived from human ACADSB |
| Specificity | This antibody detects endogenous levels of ACADSB at Human, Mouse, Rat |
Additional Info
| Function | Short and branched chain specific acyl-CoA dehydrogenase that catalyzes the removal of one hydrogen from C-2 and C-3 of the fatty acyl-CoA thioester, resulting in the formation of trans-2-enoyl-CoA. Among the different mitochondrial acyl-CoA dehydrogenases, acts specifically on short and branched chain acyl-CoA derivatives such as (S)-2-methylbutyryl-CoA as well as short straight chain acyl-CoAs such as butyryl-CoA. Plays an important role in the metabolism of L-isoleucine by catalyzing the dehydrogenation of 2-methylbutyryl-CoA, one of the steps of the L-isoleucine catabolic pathway. Can also act on valproyl-CoA, a metabolite of valproic acid, an antiepileptic drug. |
| Protein Name | Short/Branched Chain Specific Acyl-Coa Dehydrogenase - MitochondrialSbcad2-Methyl Branched Chain Acyl-Coa Dehydrogenase2-Mebcad2-Methylbutyryl-Coenzyme A Dehydrogenase2-Methylbutyryl-Coa Dehydrogenase |
| Database Links | Reactome: R-HSA-70895Reactome: R-HSA-9837999 |
| Cellular Localisation | Mitochondrion Matrix |
| Alternative Antibody Names | Anti-Short/Branched Chain Specific Acyl-Coa Dehydrogenase - Mitochondrial antibodyAnti-Sbcad antibodyAnti-2-Methyl Branched Chain Acyl-Coa Dehydrogenase antibodyAnti-2-Mebcad antibodyAnti-2-Methylbutyryl-Coenzyme A Dehydrogenase antibodyAnti-2-Methylbutyryl-Coa Dehydrogenase antibodyAnti-ACADSB antibody |
Information sourced from Uniprot.org