| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
ACADSB |
| Gene ID: |
36 |
| Uniprot ID: |
ACDSB_HUMAN |
| Specificity: |
This antibody detects endogenous levels of ACADSB at Human, Mouse, Rat |
| Immunogen: |
Synthesized peptide derived from human ACADSB |
| Function | Short and branched chain specific acyl-CoA dehydrogenase that catalyzes the removal of one hydrogen from C-2 and C-3 of the fatty acyl-CoA thioester, resulting in the formation of trans-2-enoyl-CoA. Among the different mitochondrial acyl-CoA dehydrogenases, acts specifically on short and branched chain acyl-CoA derivatives such as (S)-2-methylbutyryl-CoA as well as short straight chain acyl-CoAs such as butyryl-CoA. Plays an important role in the metabolism of L-isoleucine by catalyzing the dehydrogenation of 2-methylbutyryl-CoA, one of the steps of the L-isoleucine catabolic pathway. Can also act on valproyl-CoA, a metabolite of valproic acid, an antiepileptic drug. |
| Protein Name | Short/Branched Chain Specific Acyl-Coa Dehydrogenase - MitochondrialSbcad2-Methyl Branched Chain Acyl-Coa Dehydrogenase2-Mebcad2-Methylbutyryl-Coenzyme A Dehydrogenase2-Methylbutyryl-Coa Dehydrogenase |
| Database Links | Reactome: R-HSA-70895 |
| Cellular Localisation | Mitochondrion Matrix |
| Alternative Antibody Names | Anti-Short/Branched Chain Specific Acyl-Coa Dehydrogenase - Mitochondrial antibodyAnti-Sbcad antibodyAnti-2-Methyl Branched Chain Acyl-Coa Dehydrogenase antibodyAnti-2-Mebcad antibodyAnti-2-Methylbutyryl-Coenzyme A Dehydrogenase antibodyAnti-2-Methylbutyryl-Coa Dehydrogenase antibodyAnti-ACADSB antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
