• Immunohistochemistry analysis of ACADSB in paraffin-embedded mouse spinal cord using ACADSB Rabbit polyclonal antibody (STJ117213) at dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7. 2 before commencing with immunohistochemistry staining protocol.
  • Immunohistochemistry analysis of ACADSB in paraffin-embedded human breast cancer using ACADSB Rabbit polyclonal antibody (STJ117213) at dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7. 2 before commencing with immunohistochemistry staining protocol.
  • Immunohistochemistry analysis of ACADSB in paraffin-embedded rat brain using ACADSB Rabbit polyclonal antibody (STJ117213) at dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7. 2 before commencing with immunohistochemistry staining protocol.

Anti-ACADSB antibody (133-432) (STJ117213)

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STJ117213

£169.50 - £449.50
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Host: Rabbit
Applications: IHC
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-ACADSB (133-432) is suitable for use in Immunohistochemistry research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: IHC-P 1:50-1:200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: ACADSB
Gene ID: 36
Uniprot ID: ACDSB_HUMAN
Immunogen Region: 133-432
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 133-432 of human ACADSB (NP_001600.1).
Immunogen Sequence: ASVAVFCEIQNTLINTLIRK HGTEEQKATYLPQLTTEKVG SFCLSEAGAGSDSFALKTRA DKEGDYYVLNGSKMWISSAE HAGLFLVMANVDPTIGYKGI TSFLVDRDTPGLHIGKPENK LGLRASSTCPLTFENVKVPE ANILGQIGHGYKYAIGSLNE GRIGIAAQMLGLAQGCFDYT IPYIKERIQFGKRLFDFQGL QHQVAHVATQLEAARLLTYN AARLLEAGKPFIKEASMAK
Tissue Specificity Ubiquitously expressed.
Function Short and branched chain specific acyl-CoA dehydrogenase that catalyzes the removal of one hydrogen from C-2 and C-3 of the fatty acyl-CoA thioester, resulting in the formation of trans-2-enoyl-CoA. Among the different mitochondrial acyl-CoA dehydrogenases, acts specifically on short and branched chain acyl-CoA derivatives such as (S)-2-methylbutyryl-CoA as well as short straight chain acyl-CoAs such as butyryl-CoA. Plays an important role in the metabolism of L-isoleucine by catalyzing the dehydrogenation of 2-methylbutyryl-CoA, one of the steps of the L-isoleucine catabolic pathway. Can also act on valproyl-CoA, a metabolite of valproic acid, an antiepileptic drug.
Protein Name Short/Branched Chain Specific Acyl-Coa Dehydrogenase - Mitochondrial
Sbcad
2-Methyl Branched Chain Acyl-Coa Dehydrogenase
2-Mebcad
2-Methylbutyryl-Coenzyme A Dehydrogenase
2-Methylbutyryl-Coa Dehydrogenase
Database Links Reactome: R-HSA-70895
Cellular Localisation Mitochondrion Matrix
Alternative Antibody Names Anti-Short/Branched Chain Specific Acyl-Coa Dehydrogenase - Mitochondrial antibody
Anti-Sbcad antibody
Anti-2-Methyl Branched Chain Acyl-Coa Dehydrogenase antibody
Anti-2-Mebcad antibody
Anti-2-Methylbutyryl-Coenzyme A Dehydrogenase antibody
Anti-2-Methylbutyryl-Coa Dehydrogenase antibody
Anti-ACADSB antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance