Anti-ACAD11 antibody (1-230) (STJ118593)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal ACAD11 (1-230) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ACAD11 |
| Gene ID | 84129 |
| Uniprot ID | ACD11_HUMAN |
| Immunogen Region | 1-230 |
| Immunogen Sequence | MKPGATGESDLAEVLPQHKF DSKSLEAYLNQHLSGFGAER EATLTIAQYRAGKSNPTFYL QKGFQTYVLRKKPPGSLLPK AHQIDREFKVQKALFSIGFP VPKPILYCSDTSVIGTEFYV MEHVQGRIFRDLTIPGLSPA ERSAIYVATVETLAQLHSLN IQSLQLEGYGIGAGYCKRQV STWTKQYQAAAHQDIPAMQQ LSEWLMKNLPDNDNEENLIH GDFRLDNIVF |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-230 of human ACAD11 (NP_115545.3). |
Additional Info
| Tissue Specificity | Widely expressed with highest levels in brain followed by liver, heart and kidney. |
| Function | Acyl-CoA dehydrogenase, that exhibits maximal activity towards saturated C22-CoA. Probably participates in beta-oxydation and energy production but could also play a role in the metabolism of specific fatty acids to control fatty acids composition of cellular lipids in brain (Probable). |
| Protein Name | Acyl-Coa Dehydrogenase Family Member 11Acad-11 |
| Database Links | Reactome: R-HSA-77289 |
| Cellular Localisation | PeroxisomeMitochondrion MembraneHas Been Detected Associated With Mitochondrial MembraneBut No MatrixIn Kidney And CerebellumAs Well As In A Neuroblastoma Cell LineBut Not In Skin FibroblastsWhere It Is Observed In Cytoplasmic VesiclesNo Mitochondrial Targeting Signals Could Be Predicted For Any Known IsoformIncluding A Putative Isoform Starting At Met-316 |
| Alternative Antibody Names | Anti-Acyl-Coa Dehydrogenase Family Member 11 antibodyAnti-Acad-11 antibodyAnti-ACAD11 antibody |
Information sourced from Uniprot.org