Anti-ABI3 antibody (197-366 aa) [SRM5392] (STJ11107302)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal ABI3 (197-366 aa) antibody for use in WB and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | SRM5392 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:1000-1:4000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.09% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ABI3 |
| Gene ID | 51225 |
| Uniprot ID | ABI3_HUMAN |
| Immunogen Region | 197-366 aa |
| Immunogen Sequence | VPDGRLSAASSAFSLASAGS AEGVGGAPTPKGQAAPPAPP LPSSLDPPPPPAAVEVFQRP PTLEELSPPPPDEELPLPLD LPPPPPLDGDELGLPPPPPG FGPDEPSWVPASYLEKVVTL YPYTSQKDNELSFSEGTVIC VTRRYSDGWCEGVSSEGTGF FPGNYVEPSC |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 197-366 of human ABI3 (NP_057512.2). |
Additional Info
| Tissue Specificity | Expressed in heart, lung, liver, pancreas, kidney, placenta and at low levels in brain and skeletal muscle. |
| Function | May inhibit tumor metastasis. In vitro, reduces cell motility. |
| Protein Name | Abi Gene Family Member 3New Molecule Including Sh3Nesh |
| Database Links | |
| Cellular Localisation | CytoplasmColocalizes With Pak2 At Leading Edge Of Cells |
| Alternative Antibody Names | Anti-Abi Gene Family Member 3 antibodyAnti-New Molecule Including Sh3 antibodyAnti-Nesh antibodyAnti-ABI3 antibodyAnti-NESH antibody |
Information sourced from Uniprot.org