Anti-Abhd6 antibody [SRM15027] (STJ11109757)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenRecombinant protein (or fragment).This information is considered to be commercially sensitive.
General Information
| Short Description | Rabbit monoclonal Abhd6 antibody for use in WB, IF-F, IHC-P and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF-F/IHC-P/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | SRM15027 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity purification |
| Dilution Range | WB, 1:6000-1:24000IF-F, 1:100-1:400IHC-P, 1:100-1:400ELISA, Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | Abhd6 |
| Gene ID | 66082 |
| Uniprot ID | ABHD6_MOUSE |
| Immunogen | Recombinant protein (or fragment).This information is considered to be commercially sensitive. |
Additional Info
| Tissue Specificity | Widely expressed with higher expression in small intestine, liver and brown adipose tissue. In brain, expressed postsynaptically in cortical neurons but not detected in microglia (at protein level). |
| Function | Lipase that preferentially hydrolysis medium-chain saturated monoacylglycerols including 2-arachidonoylglycerol. Through 2-arachidonoylglycerol degradation may regulate endocannabinoid signaling pathways. Also has a lysophosphatidyl lipase activity with a preference for lysophosphatidylglycerol among other lysophospholipids. Also able to degrade bis(monoacylglycero)phosphate (BMP) and constitutes the major enzyme for BMP catabolism. BMP, also known as lysobisphosphatidic acid, is enriched in late endosomes and lysosomes and plays a key role in the formation of intraluminal vesicles and in lipid sorting. |
| Protein Name | Monoacylglycerol Lipase Abhd62-Arachidonoylglycerol HydrolaseAbhydrolase Domain-Containing Protein 6 |
| Database Links | Reactome: R-MMU-426048 |
| Cellular Localisation | Late Endosome MembraneSingle-Pass Type Ii Membrane ProteinLysosome MembraneMitochondrion Membrane |
| Alternative Antibody Names | Anti-Monoacylglycerol Lipase Abhd6 antibodyAnti-2-Arachidonoylglycerol Hydrolase antibodyAnti-Abhydrolase Domain-Containing Protein 6 antibodyAnti-Abhd6 antibody |
Information sourced from Uniprot.org