Anti-Abhd6 antibody [SRM13570] (STJ11108300)

SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenRecombinant protein (or fragment).This information is considered to be commercially sensitive.
STJ11108300
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General Information

Short DescriptionRabbit monoclonal Abhd6 antibody for use in WB, IF-F, IHC-P and ELISA in mouse samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsWB/IF-F/IHC-P/ELISA
HostRabbit
ReactivityMouse
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityMonoclonal
Clone IDSRM13570
IsotypeIgG
ConjugationUnconjugated
ConcentrationLot specific
PurificationAffinity purification
Dilution RangeWB, 1:5000-1:20000
IF-F, 1:100-1:400
IHC-P, 1:600-1:3000
ELISA, Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
FormulationPBS with 0.09% Sodium Azide, 0.05% BSA, 50% Glycerol, pH7.3.
Storage InstructionStore at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Target Information

Gene SymbolAbhd6
Gene ID66082
Uniprot IDABHD6_MOUSE
ImmunogenRecombinant protein (or fragment).This information is considered to be commercially sensitive.
Immunogen SequenceMouse

Additional Info

Function Lipase that preferentially hydrolysis medium-chain saturated monoacylglycerols including 2-arachidonoylglycerol. Through 2-arachidonoylglycerol degradation may regulate endocannabinoid signaling pathways. Also has a lysophosphatidyl lipase activity with a preference for lysophosphatidylglycerol among other lysophospholipids. Also able to degrade bis(monoacylglycero)phosphate (BMP) and constitutes the major enzyme for BMP catabolism. BMP, also known as lysobisphosphatidic acid, is enriched in late endosomes and lysosomes and plays a key role in the formation of intraluminal vesicles and in lipid sorting.
Protein Name Monoacylglycerol Lipase Abhd6
2-Arachidonoylglycerol Hydrolase
Abhydrolase Domain-Containing Protein 6
Database Links Reactome: R-MMU-426048
Cellular Localisation Late Endosome Membrane
Single-Pass Type Ii Membrane Protein
Lysosome Membrane
Mitochondrion Membrane
Alternative Antibody Names Anti-Monoacylglycerol Lipase Abhd6 antibody
Anti-2-Arachidonoylglycerol Hydrolase antibody
Anti-Abhydrolase Domain-Containing Protein 6 antibody
Anti-Abhd6 antibody

Information sourced from Uniprot.org

Citations

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