Immunofluorescence analysis of MCF-7 cells, using ABHD2 Antibody. The picture on the right is blocked with the synthesized peptide.

Anti-ABHD2 antibody (251-300 aa) (STJ91424)

SKU:
STJ91424
€60.00 - €315.00
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Host: Rabbit
Applications: WB/IF/ELISA
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit polyclonal antibody anti-Monoacylglycerol lipase ABHD2 (251-300 aa) is suitable for use in Western Blot, Immunofluorescence and ELISA research applications.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IF 1:200-1:1000
ELISA 1:40000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: ABHD2
Gene ID: 11057
Uniprot ID: ABHD2_HUMAN
Immunogen Region: 251-300 aa
Specificity: ABHD2 Polyclonal Antibody detects endogenous levels of ABHD2 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human ABHD2 at the amino acid range 251-300
Function Progesterone-dependent acylglycerol lipase that catalyzes hydrolysis of endocannabinoid arachidonoylglycerol (AG) from cell membrane. Acts as a progesterone receptor: progesterone-binding activates the acylglycerol lipase activity, mediating degradation of 1-arachidonoylglycerol (1AG) and 2-arachidonoylglycerol (2AG) to glycerol and arachidonic acid (AA). Also displays an ester hydrolase activity against acetyl ester, butanoate ester and hexadecanoate ester. Plays a key role in sperm capacitation in response to progesterone by mediating degradation of 2AG, an inhibitor of the sperm calcium channel CatSper, leading to calcium influx via CatSper and sperm activation. May also play a role in smooth muscle cells migration.
Protein Name Monoacylglycerol Lipase Abhd2
2-Arachidonoylglycerol Hydrolase
Abhydrolase Domain-Containing Protein 2
Acetylesterase
Lung Alpha/Beta Hydrolase 2
Progesterone-Sensitive Lipase
Protein Phps1-2
Cellular Localisation Cell Projection
Cilium
Flagellum Membrane
Single-Pass Type Ii Membrane Protein
Cell Membrane
Alternative Antibody Names Anti-Monoacylglycerol Lipase Abhd2 antibody
Anti-2-Arachidonoylglycerol Hydrolase antibody
Anti-Abhydrolase Domain-Containing Protein 2 antibody
Anti-Acetylesterase antibody
Anti-Lung Alpha/Beta Hydrolase 2 antibody
Anti-Progesterone-Sensitive Lipase antibody
Anti-Protein Phps1-2 antibody
Anti-ABHD2 antibody
Anti-LABH2 antibody

Information sourced from Uniprot.org

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