Anti-ABHD14B antibody (188-200) (STJ72792)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-ABHD14B (188-200) is suitable for use in ELISA and Western Blot research applications. |
| Applications | Pep-ELISA/WB |
| Host | Goat |
| Reactivity | Human/Mouse/Rat/Dog/Pig/Cow |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:64000.WB: Approx 24kDa band observed in Human, Mouse, and Rat Liver lysates (calculated MW of 22.3kDa according to NP_116139.1). Recommended concentration: 0.3-1µg/ml. |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | ABHD14B |
| Gene ID | 84836 |
| Uniprot ID | ABHEB_HUMAN |
| Accession Number | NP_116139.1 |
| Immunogen Region | 188-200 |
| Immunogen Sequence | HPCYLDKPEEWHT |
| Specificity | Reported variants represent identical protein: NP_116139.1, NP_001139786.1. This antibody is expected to NOT cross-react with ABHD14A. |
Additional Info
| Function | Acts as an atypical protein-lysine deacetylase in vitro. Catalyzes the deacetylation of lysine residues using CoA as substrate, generating acetyl-CoA and the free amine of protein-lysine residues. Additional experiments are however required to confirm the protein-lysine deacetylase activity in vivo (Probable). Has hydrolase activity towards various surrogate p-nitrophenyl (pNp) substrates, such as pNp-butyrate, pNp-acetate and pNp-octanoate in vitro, with a strong preference for pNp-acetate. May activate transcription. |
| Protein Name | Putative Protein-Lysine Deacylase Abhd14bAlpha/Beta Hydrolase Domain-Containing Protein 14bAbhydrolase Domain-Containing Protein 14bCcg1-Interacting Factor B |
| Database Links | Reactome: R-HSA-156584 |
| Cellular Localisation | CytoplasmNucleusPredominantly Cytoplasmic |
| Alternative Antibody Names | Anti-Putative Protein-Lysine Deacylase Abhd14b antibodyAnti-Alpha/Beta Hydrolase Domain-Containing Protein 14b antibodyAnti-Abhydrolase Domain-Containing Protein 14b antibodyAnti-Ccg1-Interacting Factor B antibodyAnti-ABHD14B antibodyAnti-CIB antibody |
Information sourced from Uniprot.org