||Human, Mouse, Rat
||FOR RESEARCH USE ONLY (RUO).
||Rabbit polyclonal antibody anti-Atp-Binding Cassette Sub-Family G Member 5 (250-330) is suitable for use in Western Blot and ELISA research applications.
||PBS, 50% Glycerol and 0.02% Sodium Azide.
||The antibody was affinity-purified from rabbit anti-serum by affinity-chromatography.
||WB 1:500-2000ELISA 1:5000-20000
||Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
||ABCG5 polyclonal antibody (Atp-Binding Cassette Sub-Family G Member 5) binds to endogenous Atp-Binding Cassette Sub-Family G Member 5 at the amino acid region 250-330.
||Synthesized peptide derived from human protein at aa range 250-330
| Post Translational Modifications || N-glycosylated. |
| Function || ABCG5 and ABCG8 form an obligate heterodimer that mediates Mg(2+)- and ATP-dependent sterol transport across the cell membrane. Plays an essential role in the selective transport of dietary plant sterols and cholesterol in and out of the enterocytes and in the selective sterol excretion by the liver into bile. Required for normal sterol homeostasis. The heterodimer with ABCG8 has ATPase activity. |
| Protein Name || Atp-Binding Cassette Sub-Family G Member 5Sterolin-1 |
| Database Links || Reactome: R-HSA-1369062Reactome: R-HSA-5679090Reactome: R-HSA-5679096Reactome: R-HSA-9029569 |
| Cellular Localisation || Cell MembraneMulti-Pass Membrane ProteinApical Cell Membrane |
| Alternative Antibody Names || Anti-Atp-Binding Cassette Sub-Family G Member 5 antibodyAnti-Sterolin-1 antibodyAnti-ABCG5 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance