| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-ATP-binding cassette sub-family F member 1 (760-840 aa) is suitable for use in Western Blot and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:2000ELISA 1:10000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ABCF1 |
| Gene ID: | 23 |
| Uniprot ID: | ABCF1_HUMAN |
| Immunogen Region: | 760-840 aa |
| Specificity: | ABCF1 Polyclonal Antibody detects endogenous levels of ABCF1 protein. |
| Immunogen: | Synthesized peptide derived from ABCF1 at the amino acid range 760-840 |
| Post Translational Modifications | Isoform 2 is phosphorylated at phosphoserine and phosphothreonine. Isoform 2 phosphorylation on Ser-109 and Ser-140 by CK2 inhibits association of EIF2 with ribosomes. |
| Function | Isoform 2 is required for efficient Cap- and IRES-mediated mRNA translation initiation. Isoform 2 is not involved in the ribosome biogenesis. |
| Protein Name | Atp-Binding Cassette Sub-Family F Member 1Atp-Binding Cassette 50Tnf-Alpha-Stimulated Abc Protein |
| Database Links | Reactome: R-HSA-382556 |
| Cellular Localisation | Isoform 2: CytoplasmNucleusNucleoplasmNucleus Envelope |
| Alternative Antibody Names | Anti-Atp-Binding Cassette Sub-Family F Member 1 antibodyAnti-Atp-Binding Cassette 50 antibodyAnti-Tnf-Alpha-Stimulated Abc Protein antibodyAnti-ABCF1 antibodyAnti-ABC50 antibody |
Information sourced from Uniprot.org
