• Western blot analysis of ABCC2 Antibody. The lane on the right is blocked with the ABCC2 peptide.
  • Western blot analysis of the lysates from HeLa cells using ABCC2 antibody.
  • Western blot analysis of 3T3 cells using MRP2 Polyclonal Antibody diluted at 1:1000

Anti-ABCC2 antibody (960-1040 Internal) (STJ94205)

SKU:
STJ94205

Current Stock:
Host: Rabbit
Applications: WB, ELISA
Reactivity: Human, Rat, Mouse
Note: FOR RESEARCH USE ONLY (RUO).
Short Description: Rabbit polyclonal antibody anti-Atp-Binding Cassette Sub-Family C Member 2 (960-1040 Internal) is suitable for use in Western Blot and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS, 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit anti-serum by affinity-chromatography.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
ELISA 1:10000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: ABCC2
Gene ID: 1244
Uniprot ID: MRP2_HUMAN
Immunogen Region: 960-1040 Internal
Specificity: ABCC2 polyclonal antibody (Atp-Binding Cassette Sub-Family C Member 2) binds to endogenous Atp-Binding Cassette Sub-Family C Member 2 at the amino acid region 960-1040 Internal.
Immunogen: The antiserum was produced against synthesized peptide derived from human ABCC2 at amino acid range 991-1040
Function ATP-dependent transporter of the ATP-binding cassette (ABC) family that binds and hydrolyzes ATP to enable active transport of various substrates including many drugs, toxicants and endogenous compound across cell membranes. Transports a wide variety of conjugated organic anions such as sulfate-, glucuronide- and glutathione (GSH)-conjugates of endo- and xenobiotics substrates. Mediates hepatobiliary excretion of mono- and bis-glucuronidated bilirubin molecules and therefore play an important role in bilirubin detoxification. Mediates also hepatobiliary excretion of others glucuronide conjugates such as 17beta-estradiol 17-glucosiduronic acid and leukotriene C4. Transports sulfated bile salt such as taurolithocholate sulfate. Transport various anticancer drugs, such as anthracycline, vinca alkaloid and methotrexate and HIV-drugs such as protease inhibitors. Confers resistance to several anti-cancer drugs including cisplatin, doxorubicin, epirubicin, methotrexate, etoposide and vincristine.
Protein Name Atp-Binding Cassette Sub-Family C Member 2
Canalicular Multidrug Resistance Protein
Canalicular Multispecific Organic Anion Transporter 1
Multidrug Resistance-Associated Protein 2
Database Links Reactome: R-HSA-189483
Reactome: R-HSA-382556
Reactome: R-HSA-5679001
Cellular Localisation Apical Cell Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Atp-Binding Cassette Sub-Family C Member 2 antibody
Anti-Canalicular Multidrug Resistance Protein antibody
Anti-Canalicular Multispecific Organic Anion Transporter 1 antibody
Anti-Multidrug Resistance-Associated Protein 2 antibody
Anti-ABCC2 antibody
Anti-CMOAT antibody
Anti-CMOAT1 antibody
Anti-CMRP antibody
Anti-MRP2 antibody

Information sourced from Uniprot.org

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