Anti-ABCC10 antibody (800-850 aa) (STJ13100679)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic peptide from aa region 800-850 of human ABCC10 conjugated to an immunogenic carrier protein was used as the antigen.
General Information
| Short Description | Rabbit polyclonal anti-ABCC10 (800-850 aa) for use in IHC and WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/WB |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | IgG purified |
| Dilution Range | IHC, WB (recombinant protein). A dilution of 1:300 to 1:2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications. |
| Formulation | Lyophilised |
| Storage Instruction | Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
Target Information
| Gene Symbol | ABCC10 |
| Gene ID | 89845 |
| Uniprot ID | MRP7_HUMAN |
| Immunogen | A synthetic peptide from aa region 800-850 of human ABCC10 conjugated to an immunogenic carrier protein was used as the antigen. |
| Immunogen Region | 800-850 aa |
| Specificity | Specific for ABCC10. |
Additional Info
| Function | ATP-dependent transporter of the ATP-binding cassette (ABC) family that actively extrudes physiological compounds, and xenobiotics from cells. Lipophilic anion transporter that mediates ATP-dependent transport of glucuronide conjugates such as estradiol-17-beta-o-glucuronide and GSH conjugates such as leukotriene C4 (LTC4). May contribute to regulate the transport of organic compounds in testes across the blood-testis-barrier (Probable). Mediates multidrug resistance (MDR) in cancer cells by preventing the intracellular accumulation of certain antitumor drugs, such as, docetaxel and paclitaxel. Does not transport glycocholic acid, taurocholic acid, MTX, folic acid, cAMP, or cGMP. |
| Protein Name | Atp-Binding Cassette Sub-Family C Member 10Multidrug Resistance-Associated Protein 7 |
| Database Links | Reactome: R-HSA-382556 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinBasolateral Cell MembraneBasal Cell MembraneLocalized To The Basal Membrane Of Sertoli Cells |
| Alternative Antibody Names | Anti-Atp-Binding Cassette Sub-Family C Member 10 antibodyAnti-Multidrug Resistance-Associated Protein 7 antibodyAnti-ABCC10 antibodyAnti-MRP7 antibodyAnti-SIMRP7 antibody |
Information sourced from Uniprot.org