Anti-ABCA5 antibody (1240-1320 aa) (STJ190578)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human protein at the amino acid range 1240-1320
General Information
| Short Description | Rabbit polyclonal anti-Cholesterol transporter ABCA5 (1240-1320 aa) for use in WB and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ABCA5 |
| Gene ID | 23461 |
| Uniprot ID | ABCA5_HUMAN |
| Immunogen | Synthesized peptide derived from the human protein at the amino acid range 1240-1320 |
| Immunogen Region | 1240-1320 aa |
| Specificity | ABCA5 Polyclonal Antibody detects endogenous levels of protein. |
Additional Info
| Post Translational Modifications | N-glycosylated. |
| Function | Cholesterol efflux transporter in macrophages that is responsible for APOAI/high-density lipoproteins (HDL) formation at the plasma membrane under high cholesterol levels and participates in reverse cholesterol transport. May play a role in the processing of autolysosomes. |
| Protein Name | Cholesterol Transporter Abca5Atp-Binding Cassette Sub-Family A Member 5 |
| Database Links | Reactome: R-HSA-1369062 |
| Cellular Localisation | Golgi Apparatus MembraneMulti-Pass Membrane ProteinLysosome MembraneLate Endosome MembraneCell MembraneLocalized At Cell Membrane Under High Cholesterol Levels |
| Alternative Antibody Names | Anti-Cholesterol Transporter Abca5 antibodyAnti-Atp-Binding Cassette Sub-Family A Member 5 antibodyAnti-ABCA5 antibodyAnti-KIAA1888 antibody |
Information sourced from Uniprot.org