Anti-ABCA1 antibody (STJ192951)


Current Stock:
Host: Rabbit
Applications: WB, ELISA
Reactivity: Human, Mouse
Short Description: Rabbit polyclonal antibody anti-Phospholipid-Transporting Atpase Abca1 is suitable for use in Western Blot and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS, 50% Glycerol and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit anti-serum by affinity-chromatography.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
ELISA 1:5000-20000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: ABCA1
Gene ID: 19
Specificity: ABCA1 polyclonal antibody (Phospholipid-Transporting Atpase Abca1) binds to endogenous Phospholipid-Transporting Atpase Abca1.
Immunogen: Synthesized peptide derived from part region of human protein
Post Translational Modifications Phosphorylation on Ser-2054 regulates phospholipid efflux. Palmitoylated by ZDHHC8. Palmitoylation is essential for localization to the plasma membrane.
Function Catalyzes the translocation of specific phospholipids from the cytoplasmic to the extracellular/lumenal leaflet of membrane coupled to the hydrolysis of ATP. Thereby, participates in phospholipid transfer to apoliproteins to form nascent high density lipoproteins/HDLs. Transports preferentially phosphatidylcholine over phosphatidylserine. May play a similar role in the efflux of intracellular cholesterol to apoliproteins and the formation of nascent high density lipoproteins/HDLs.
Protein Name Phospholipid-Transporting Atpase Abca1
Atp-Binding Cassette Sub-Family A Member 1
Atp-Binding Cassette Transporter 1
Atp-Binding Cassette 1
Cholesterol Efflux Regulatory Protein
Database Links Reactome: R-HSA-1989781
Reactome: R-HSA-5682113
Reactome: R-HSA-8963896
Reactome: R-HSA-9029569
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Phospholipid-Transporting Atpase Abca1 antibody
Anti-Atp-Binding Cassette Sub-Family A Member 1 antibody
Anti-Atp-Binding Cassette Transporter 1 antibody
Anti-Abc-1 antibody
Anti-Atp-Binding Cassette 1 antibody
Anti-Cholesterol Efflux Regulatory Protein antibody
Anti-ABCA1 antibody
Anti-ABC1 antibody
Anti-CERP antibody

Information sourced from

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