Immunohistochemistry analysis of AASS in paraffin-embedded rat liver using AASS Rabbit polyclonal antibody (STJ11105411) at dilution of 1:100 (40x lens). Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6. 0 before commencing with immunohistochemistry staining protocol.

Anti-AASS antibody (480-600) (STJ11105411)

⇓ Datasheet ⇓ SDS
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
STJ11105411
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General Information

Short DescriptionRabbit polyclonal Alpha-Aminoadipic Semialdehyde Synthase-Mitochondrial (480-600) antibody for use in WB, IHC-P and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsWB/IHC-P/ELISA
HostRabbit
ReactivityHuman/Mouse/Rat
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityPolyclonal
IsotypeIgG
ConjugationUnconjugated
ConcentrationLot specific
PurificationAffinity purification
Dilution RangeWB:1:50-1:200
IHC-P:1:50-1:200
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
FormulationPBS with 0.05% Proclin300, 50% Glycerol, pH 7.3.
Storage InstructionStore at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Target Information

Gene SymbolAASS
Gene ID10157
Uniprot IDAASS_HUMAN
Immunogen Region480-600
Immunogen SequenceRRKVLVLGSGYISEPVLEYL SRDGNIEITVGSDMKNQIEQ LGKKYNINPVSMDICKQEEK LGFLVAKQDLVISLLPYVLH PLVAKACITNKVNMVTASYI TPALKELEKSVEDAGITIIG E
SpecificityRecombinant fusion protein containing a sequence corresponding to amino acids 480-600 of human AASS (NP_005754.2).

Additional Info

Tissue Specificity Expressed in all 16 tissues examined with highest expression in the liver.
Function Bifunctional enzyme that catalyzes the first two steps in lysine degradation.
Protein Name Alpha-Aminoadipic Semialdehyde Synthase - Mitochondrial
Lkr/Sdh Includes - Lysine Ketoglutarate Reductase
Lkr
Lor - Saccharopine Dehydrogenase
Sdh
Database Links Reactome: R-HSA-71064
Cellular Localisation Mitochondrion
Alternative Antibody Names Anti-Alpha-Aminoadipic Semialdehyde Synthase - Mitochondrial antibody
Anti-Lkr/Sdh Includes - Lysine Ketoglutarate Reductase antibody
Anti-Lkr antibody
Anti-Lor - Saccharopine Dehydrogenase antibody
Anti-Sdh antibody
Anti-AASS antibody

Information sourced from Uniprot.org

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