Anti-AADAT antibody (34-429) (STJ115056)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal AADAT (34-429) antibody for use in WB and ELISA in rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:1000-1:5000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | AADAT |
| Gene ID | 51166 |
| Uniprot ID | AADAT_HUMAN |
| Immunogen Region | 34-429 |
| Immunogen Sequence | PKSMISLAGGLPNPNMFPFK TAVITVENGKTIQFGEEMMK RALQYSPSAGIPELLSWLKQ LQIKLHNPPTIHYPPSQGQM DLCVTSGSQQGLCKVFEMII NPGDNVLLDEPAYSGTLQSL HPLGCNIINVASDESGIVPD SLRDILSRWKPEDAKNPQKN TPKFLYTVPNGNNPTGNSLT SERKKEIYELARKYDFLIIE DDPYYFLQFNKFRVPTFLSM DVDGRVIRADSFSKIISSG |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 34-429 of human AADAT (NP_001273611.1). |
Additional Info
| Tissue Specificity | Higher expression in the liver. Also found in heart, brain, kidney, pancreas, prostate, testis and ovary. |
| Function | Transaminase with broad substrate specificity. Has transaminase activity towards aminoadipate, kynurenine, methionine and glutamate. Shows activity also towards tryptophan, aspartate and hydroxykynurenine. Accepts a variety of oxo-acids as amino-group acceptors, with a preference for 2-oxoglutarate, 2-oxocaproic acid, phenylpyruvate and alpha-oxo-gamma-methiol butyric acid. Can also use glyoxylate as amino-group acceptor (in vitro). |
| Protein Name | Kynurenine/Alpha-Aminoadipate Aminotransferase - MitochondrialKat/Aadat2-Aminoadipate Aminotransferase2-Aminoadipate TransaminaseAlpha-Aminoadipate AminotransferaseAadatGlycine Transaminase AadatKynurenine Aminotransferase IiKynurenine--Glyoxylate Transaminase AadatKynurenine--Oxoglutarate Aminotransferase IiKynurenine--Oxoglutarate Transaminase 2Kynurenine--Oxoglutarate Transaminase IiMethionine--Glyoxylate Transaminase Aadat |
| Database Links | Reactome: R-HSA-71064Reactome: R-HSA-71240 |
| Cellular Localisation | Mitochondrion |
| Alternative Antibody Names | Anti-Kynurenine/Alpha-Aminoadipate Aminotransferase - Mitochondrial antibodyAnti-Kat/Aadat antibodyAnti-2-Aminoadipate Aminotransferase antibodyAnti-2-Aminoadipate Transaminase antibodyAnti-Alpha-Aminoadipate Aminotransferase antibodyAnti-Aadat antibodyAnti-Glycine Transaminase Aadat antibodyAnti-Kynurenine Aminotransferase Ii antibodyAnti-Kynurenine--Glyoxylate Transaminase Aadat antibodyAnti-Kynurenine--Oxoglutarate Aminotransferase Ii antibodyAnti-Kynurenine--Oxoglutarate Transaminase 2 antibodyAnti-Kynurenine--Oxoglutarate Transaminase Ii antibodyAnti-Methionine--Glyoxylate Transaminase Aadat antibodyAnti-AADAT antibodyAnti-KAT2 antibodyAnti-KYAT2 antibody |
Information sourced from Uniprot.org