Anti-AAAS antibody (360-440 aa) (STJ96407)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from Aladin at the amino acid range 360-440
General Information
| Short Description | Rabbit polyclonal anti-Aladin (360-440 aa) for use in WB and ELISA in Human and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000ELISA 1:40000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | AAAS |
| Gene ID | 8086 |
| Uniprot ID | AAAS_HUMAN |
| Immunogen | Synthesized peptide derived from Aladin at the amino acid range 360-440 |
| Immunogen Region | 360-440 aa |
| Specificity | Aladin Polyclonal Antibody detects endogenous levels of Aladin protein. |
Additional Info
| Function | Plays a role in the normal development of the peripheral and central nervous system. Required for the correct localization of aurora kinase AURKA and the microtubule minus end-binding protein NUMA1 as well as a subset of AURKA targets which ensures proper spindle formation and timely chromosome alignment. |
| Protein Name | AladinAdracalin |
| Database Links | Reactome: R-HSA-1169408Reactome: R-HSA-159227Reactome: R-HSA-159230Reactome: R-HSA-159231Reactome: R-HSA-159236Reactome: R-HSA-165054Reactome: R-HSA-168271Reactome: R-HSA-168276Reactome: R-HSA-168325Reactome: R-HSA-168333Reactome: R-HSA-170822Reactome: R-HSA-180746Reactome: R-HSA-180910Reactome: R-HSA-191859Reactome: R-HSA-3108214Reactome: R-HSA-3232142Reactome: R-HSA-3301854Reactome: R-HSA-3371453Reactome: R-HSA-4085377Reactome: R-HSA-4551638Reactome: R-HSA-4570464Reactome: R-HSA-4615885Reactome: R-HSA-5578749Reactome: R-HSA-5619107Reactome: R-HSA-6784531Reactome: R-HSA-8980692Reactome: R-HSA-9609690Reactome: R-HSA-9610379Reactome: R-HSA-9705671 |
| Cellular Localisation | NucleusNuclear Pore ComplexCytoplasmCytoskeletonSpindle PoleNucleus EnvelopeIn Metaphase Cells Localizes Within The Spindle With Some Accumulation Around Spindle PolesWith The Highest Concentration Between The Centrosome And Metaphase PlateThe Localization To The Spindle Is Microtubule-Mediated |
| Alternative Antibody Names | Anti-Aladin antibodyAnti-Adracalin antibodyAnti-AAAS antibodyAnti-ADRACALA antibodyAnti-GL003 antibody |
Information sourced from Uniprot.org