Anti-A4GALT antibody (STJ190919)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from part of the human protein
General Information
| Short Description | Rabbit polyclonal anti-Lactosylceramide 4-alpha-galactosyltransferase for use in WB and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | A4GALT |
| Gene ID | 53947 |
| Uniprot ID | A4GAT_HUMAN |
| Immunogen | Synthesized peptide derived from part of the human protein |
| Specificity | A4GAT Polyclonal Antibody detects endogenous levels of protein. |
Additional Info
| Function | Catalyzes the transfer of galactose from UDP-alpha-D-galactose to lactosylceramide/beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide(d18:1(4E)) to produce globotriaosylceramide/globoside Gb3Cer (d18:1(4E)). Also able to transfer galactose to galactosylceramide/beta-D-Gal-(1<->1')-Cer. Globoside Gb3Cer is a glycosphingolipid of the globo serie, one of the major types of neutral root structures of glycosphingolipids, that constitute a significant portion of mammalian cell membranes (Probable). Globotriaosylceramide/globoside Gb3Cer in blood and tissue cell membranes is the antigen Pk of blood histogroup P. (Microbial infection) Globotriaosylceramide is one of the cellular ligands for bacterial verotoxins. |
| Protein Name | Lactosylceramide 4-Alpha-GalactosyltransferaseAlpha-1 -4-N-AcetylglucosaminyltransferaseAlpha-1 -4-GalactosyltransferaseAlpha4gal-T1Cd77 SynthaseGlobotriaosylceramide SynthaseGb3 SynthaseP1/Pk SynthaseUdp-Galactose -Beta-D-Galactosyl-Beta1-R 4-Alpha-D-Galactosyltransferase |
| Database Links | Reactome: R-HSA-9840309 |
| Cellular Localisation | Golgi Apparatus MembraneSingle-Pass Type Ii Membrane Protein |
| Alternative Antibody Names | Anti-Lactosylceramide 4-Alpha-Galactosyltransferase antibodyAnti-Alpha-1 -4-N-Acetylglucosaminyltransferase antibodyAnti-Alpha-1 -4-Galactosyltransferase antibodyAnti-Alpha4gal-T1 antibodyAnti-Cd77 Synthase antibodyAnti-Globotriaosylceramide Synthase antibodyAnti-Gb3 Synthase antibodyAnti-P1/Pk Synthase antibodyAnti-Udp-Galactose -Beta-D-Galactosyl-Beta1-R 4-Alpha-D-Galactosyltransferase antibodyAnti-A4GALT antibodyAnti-A14GALT antibodyAnti-A4GALT1 antibody |
Information sourced from Uniprot.org