![Anti-68kDa Neurofilament/NF-L antibody [SM5045] (STJA0005045)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/124x110/products/180102/403371/STJA0005045_1__00368.1738950437.png?c=1 "Anti-68kDa Neurofilament/NF-L antibody [SM5045] (STJA0005045)")
![Anti-68kDa Neurofilament/NF-L antibody [SM5045] (STJA0005045)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/1280x1280/products/180102/403371/STJA0005045_1__00368.1738950437.png?c=1 "Anti-68kDa Neurofilament/NF-L antibody [SM5045] (STJA0005045)")
Anti-68kDa Neurofilament/NF-L antibody [SM5045] (STJA0005045)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
ImmunogenSynthesized peptide derived from human Neurofilament
General Information
| Short Description | Mouse monoclonal anti-68kDa Neurofilament/NF-L for use in IHC and IF in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/IF |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | SM5045 |
| Conjugation | Unconjugated |
| Purification | The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. |
| Dilution Range | IHC/IF (H) 1:200-1:500 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Storage Instruction | Store at-20C for up to one year, and avoid repeated freeze-thaw cycles. |
Target Information
| Gene Symbol | NEFL |
| Gene ID | 4747 |
| Uniprot ID | NFL_HUMAN |
| Immunogen | Synthesized peptide derived from human Neurofilament |
Additional Info
| Function | Neurofilaments usually contain three intermediate filament proteins: NEFL, NEFM, and NEFH which are involved in the maintenance of neuronal caliber. May additionally cooperate with the neuronal intermediate filament proteins PRPH and INA to form neuronal filamentous networks. |
| Protein Name | Neurofilament Light PolypeptideNf-L68 Kda Neurofilament ProteinNeurofilament Triplet L Protein |
| Database Links | Reactome: R-HSA-438066Reactome: R-HSA-442982Reactome: R-HSA-5673001Reactome: R-HSA-9609736Reactome: R-HSA-9617324Reactome: R-HSA-9620244 |
| Cellular Localisation | Cell ProjectionAxonCytoplasmCytoskeleton |
| Alternative Antibody Names | Anti-Neurofilament Light Polypeptide antibodyAnti-Nf-L antibodyAnti-68 Kda Neurofilament Protein antibodyAnti-Neurofilament Triplet L Protein antibodyAnti-NEFL antibodyAnti-NF68 antibodyAnti-NFL antibody |
Information sourced from Uniprot.org