| Host: | Mouse |
| Applications: | IHC/IF |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Mouse monoclonal antibody anti-68kDa Neurofilament/NF-L is suitable for use in Immunohistochemistry and Immunofluorescence research applications. |
| Clonality: | Monoclonal |
| Clone ID: | SM5045 |
| Conjugation: | Unconjugated |
| Formulation: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification: | The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. |
| Dilution Range: | IHC/IF (H) 1:200-1:500 |
| Storage Instruction: | Store at-20C for up to one year, and avoid repeated freeze-thaw cycles. |
| Gene Symbol: | NEFL |
| Gene ID: | 4747 |
| Uniprot ID: | NFL_HUMAN |
| Immunogen: | Synthesized peptide derived from human Neurofilament |
| Function | Neurofilaments usually contain three intermediate filament proteins: NEFL, NEFM, and NEFH which are involved in the maintenance of neuronal caliber. May additionally cooperate with the neuronal intermediate filament proteins PRPH and INA to form neuronal filamentous networks. |
| Protein Name | Neurofilament Light Polypeptide Nf-L 68 Kda Neurofilament Protein Neurofilament Triplet L Protein |
| Database Links | Reactome: R-HSA-438066 Reactome: R-HSA-442982 Reactome: R-HSA-5673001 Reactome: R-HSA-9609736 Reactome: R-HSA-9617324 Reactome: R-HSA-9620244 |
| Cellular Localisation | Cell Projection Axon Cytoplasm Cytoskeleton |
| Alternative Antibody Names | Anti-Neurofilament Light Polypeptide antibody Anti-Nf-L antibody Anti-68 Kda Neurofilament Protein antibody Anti-Neurofilament Triplet L Protein antibody Anti-NEFL antibody Anti-NF68 antibody Anti-NFL antibody |
Information sourced from Uniprot.org
![Anti-Neurofilament antibody [NF-01] (STJ16100237)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/300x300/products/148955/346588/STJ16100237_1__04312.1681998652.jpg?c=1 "Anti-Neurofilament antibody [NF-01] (STJ16100237)")
