• Western blot analysis of lysates from HepG2 cells treated with PMA 125ng/ml 30', using EPB41 Antibody. The lane on the right is blocked with the synthesized peptide.

Anti-4.1R antibody (STJ91382)

SKU:
STJ91382

Current Stock:
Host: Rabbit
Applications: WB, ELISA
Reactivity: Human, Mouse
Short Description: Rabbit polyclonal anti-4.1R antibody is suitable for use in Western Blot and ELISA.
Note: FOR RESEARCH USE ONLY (RUO).
Clonality: Polyclonal
Conjugation: Unconjugated
Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using a epitope-specific immunogen.
Storage Instruction: Store at-20°C, and avoid repeat freeze-thaw cycles.
Concentration: 1 mg/ml
Isotype: IgG
Dilution Range: WB 1:500-1:2000
ELISA 1:5000
Specificity: 4.1R polyclonal antibody detects endogenous levels of 4.1R protein.
Uniprot ID: EPB41_HUMAN
Gene ID: 2035
Gene Symbol: EPB41
Immunogen: Synthesized peptide derived from human 4.1R around the non-phosphorylation site of Y660.
Immunogen Region: 600-680 aa
Function Protein 4.1 is a major structural element of the erythrocyte membrane skeleton. It plays a key role in regulating membrane physical properties of mechanical stability and deformability by stabilizing spectrin-actin interaction. Recruits DLG1 to membranes. Required for dynein-dynactin complex and NUMA1 recruitment at the mitotic cell cortex during anaphase.
Protein Name Protein 4.1
P4.1
4.1r
Band 4.1
Epb4.1
Erythrocyte Membrane Protein Band 4.1
Database Links Reactome: R-HSA-6794361
Cellular Localisation Cytoplasm
Cytoskeleton
Cell Cortex
Nucleus
Alternative Antibody Names Anti-Protein 4.1 antibody
Anti-P4.1 antibody
Anti-4.1r antibody
Anti-Band 4.1 antibody
Anti-Epb4.1 antibody
Anti-Erythrocyte Membrane Protein Band 4.1 antibody
Anti-EPB41 antibody
Anti-E41P antibody

Information sourced from Uniprot.org

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