| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Protein 4.1 (626-675 aa) is suitable for use in Western Blot and ELISA research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-1:2000ELISA 1:5000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
EPB41 |
| Gene ID: |
2035 |
| Uniprot ID: |
EPB41_HUMAN |
| Immunogen Region: |
626-675 aa |
| Specificity: |
4.1R Polyclonal Antibody detects endogenous levels of 4.1R protein. |
| Immunogen: |
The antiserum was produced against synthesized peptide derived from the human EPB41 at the amino acid range 626-675 |
| Function | Protein 4.1 is a major structural element of the erythrocyte membrane skeleton. It plays a key role in regulating membrane physical properties of mechanical stability and deformability by stabilizing spectrin-actin interaction. Recruits DLG1 to membranes. Required for dynein-dynactin complex and NUMA1 recruitment at the mitotic cell cortex during anaphase. |
| Protein Name | Protein 4.1P4.14.1rBand 4.1Epb4.1Erythrocyte Membrane Protein Band 4.1 |
| Database Links | Reactome: R-HSA-6794361 |
| Cellular Localisation | CytoplasmCytoskeletonCell CortexNucleus |
| Alternative Antibody Names | Anti-Protein 4.1 antibodyAnti-P4.1 antibodyAnti-4.1r antibodyAnti-Band 4.1 antibodyAnti-Epb4.1 antibodyAnti-Erythrocyte Membrane Protein Band 4.1 antibodyAnti-EPB41 antibodyAnti-E41P antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
