Anti-4-1BB antibody [DM66] (STJA0038197)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenRecombinant human 4-1BB protein
General Information
| Short Description | Rabbit monoclonal anti-4-1BB for use in FC and ELISA in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | FC/ELISA |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | DM66 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity Chromatography |
| Dilution Range | FC 1:50-1:100ELISA 1:10000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3. |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | TNFRSF9 |
| Gene ID | 3604 |
| Uniprot ID | TNR9_HUMAN |
| Immunogen | Recombinant human 4-1BB protein |
Additional Info
| Tissue Specificity | Expressed on the surface of activated T-cells. |
| Function | Receptor for TNFSF9/4-1BBL. Conveys a signal that enhances CD8(+) T-cell survival, cytotoxicity, and mitochondrial activity, thereby promoting immunity against viruses and tumors (Probable). |
| Protein Name | Tumor Necrosis Factor Receptor Superfamily Member 94-1bb Ligand ReceptorCdw137T-Cell Antigen 4-1bb HomologT-Cell Antigen IlaCd Antigen Cd137 |
| Database Links | Reactome: R-HSA-5669034 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Tumor Necrosis Factor Receptor Superfamily Member 9 antibodyAnti-4-1bb Ligand Receptor antibodyAnti-Cdw137 antibodyAnti-T-Cell Antigen 4-1bb Homolog antibodyAnti-T-Cell Antigen Ila antibodyAnti-Cd Antigen Cd137 antibodyAnti-TNFRSF9 antibodyAnti-CD137 antibodyAnti-ILA antibody |
Information sourced from Uniprot.org