Anti-37530 antibody [2B8-2E6-3A8] (STJA0033450)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG1
ImmunogenSynthesized peptide derived from human Oct-2
General Information
| Short Description | Mouse monoclonal anti-37530 for use in IHC-P in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC-P |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | 2B8-2E6-3A8 |
| Isotype | IgG1 |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | Affinity Chromatography |
| Dilution Range | IHC 1:100-1:500 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3. |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | POU2F2 |
| Gene ID | 5452 |
| Uniprot ID | PO2F2_HUMAN |
| Immunogen | Synthesized peptide derived from human Oct-2 |
Additional Info
| Tissue Specificity | Isoform 3 is B-cell specific. Isoform 5 is expressed in B-cells and the immunoglobulin-expressing T-cell line MOLT-4, but not in the T-cell line BW5147. |
| Function | Transcription factor that specifically binds to the octamer motif (5'-ATTTGCAT-3'). Regulates IL6 expression in B cells with POU2AF1. Regulates transcription in a number of tissues in addition to activating immunoglobulin gene expression. Modulates transcription transactivation by NR3C1, AR and PGR. Isoform 5: Activates the U2 small nuclear RNA (snRNA) promoter. |
| Protein Name | Pou Domain - Class 2 - Transcription Factor 2Lymphoid-Restricted Immunoglobulin Octamer-Binding Protein Nf-A2Octamer-Binding Protein 2Oct-2Octamer-Binding Transcription Factor 2Otf-2 |
| Database Links | Reactome: R-HSA-6807505 |
| Cellular Localisation | CytoplasmNucleus |
| Alternative Antibody Names | Anti-Pou Domain - Class 2 - Transcription Factor 2 antibodyAnti-Lymphoid-Restricted Immunoglobulin Octamer-Binding Protein Nf-A2 antibodyAnti-Octamer-Binding Protein 2 antibodyAnti-Oct-2 antibodyAnti-Octamer-Binding Transcription Factor 2 antibodyAnti-Otf-2 antibodyAnti-POU2F2 antibodyAnti-OCT2 antibodyAnti-OTF2 antibody |
Information sourced from Uniprot.org