| Applications: | Immunodepletion/Immunocompetition |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | AMACR Blocking Peptide for STJ500073 is synthetically produced from the 50-100 sequence and is suitable for use in western blot applications. |
| Formulation: | Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice. |
| Dilution Range: | WB: IHC: 1:100ICC: 1:100IF: 1:200CFM: 1:100 |
| Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: | AMACR |
| Gene ID: | 23600 |
| Uniprot ID: | AMACR_HUMAN |
| Immunogen Region: | 50-100 |
| Specificity: | This blocking peptide is recommended for use in combination with AMACR antibody, STJ500073 |
| Immunogen: | Synthetic peptide taken within amino acid region 50-100 on human alpha-methylacyl-CoA racemase protein. |
| Function | Catalyzes the interconversion of (R)- and (S)-stereoisomers of alpha-methyl-branched-chain fatty acyl-CoA esters. Acts only on coenzyme A thioesters, not on free fatty acids, and accepts as substrates a wide range of alpha-methylacyl-CoAs, including pristanoyl-CoA, trihydroxycoprostanoyl-CoA (an intermediate in bile acid synthesis), and arylpropionic acids like the anti-inflammatory drug ibuprofen (2-(4-isobutylphenyl)propionic acid) but neither 3-methyl-branched nor linear-chain acyl-CoAs. |
| Peptide Name | Alpha-Methylacyl-Coa Racemase2-Methylacyl-Coa Racemase |
| Database Links | Reactome: R-HSA-193368Reactome: R-HSA-193775Reactome: R-HSA-389887Reactome: R-HSA-9033241 |
| Cellular Localisation | PeroxisomeMitochondrion |
| Alternative Peptide Names | Alpha-Methylacyl-Coa Racemase protein2-Methylacyl-Coa Racemase proteinAMACR protein |
Information sourced from Uniprot.org