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Rabbit Polyclonals
Polyclonal Antibodies
Rabbit Polyclonal Antibodies
High-affinity antiserum from our most widely used polyclonal hostRabbit polyclonal antibodies are raised by immunising rabbits with a target immunogen, producing an antiserum containing a heterogeneous population of immunoglobulins that recognise multiple epitopes on the same antigen. Rabbit is one of the host species across our polyclonal range, alongside goat, chicken, and guinea pig.
How it works
Raised through rabbit host immunisation
Production begins by injecting a rabbit with the target immunogen, stimulating a primary immune response. Rabbits are a long-standing host choice for polyclonal production because of their relatively large blood volume, which supports higher-yield antiserum collection over the course of an immunisation schedule. The rabbit immune system also generates antibody diversity through gene conversion and somatic hypermutation, mechanisms distinct from those used by rodents, which contribute to the high affinity and specificity associated with rabbit-derived antibodies.
Featured products
Validated rabbit polyclonal antibodies
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Anti-14-3-3 Beta/Zeta antibody (151-200 aa)
STJ91368 · WB/IHC/IF/ELISA · Human/Mouse/Rat
14-3-3 beta and zeta are adapter protein isoforms linked to mitogenic signalling and cell cycle regulation, and overexpression of the beta isoform is associated with tumour cell invasion, migration and metastasis. Validated by western blot in NIH/3T3 cell lysate. View product → |
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Anti-5-Methyl-Cytosine/5mC antibody (5mC)
STJ11101496 · DB/ELISA · Species independent
5-methylcytosine is a primary epigenetic modification in mammalian DNA, involved in gene expression, genomic imprinting and X-chromosome inactivation, with abnormal methylation implicated in cancer. Validated by dot blot against 5mC-modified and unmodified sequences. View product → |
More validated targets
Also in the range
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Anti-5HT1A antibody (200-250)
· STJ500000 · ELISA/IP/WB · Human/Mouse/Rat 5-HT1A is a serotonin receptor subtype central to serotonergic signalling in the prefrontal cortex, amygdala and hippocampus, implicated in anxiety and depression phenotypes. Validated by western blot in rat cortex. View product → |
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Anti-5-methylcytidine/m5C antibody
· STJ11103906 · DB/ELISA · Species independent m5C is an RNA modification found across mRNA, tRNA, rRNA and non-coding RNA that regulates RNA stability, processing and translation, with dysregulation implicated in cancer and other disease. Validated by dot blot against m5C and 5mC. View product → |
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Anti-2'-O-methylcytidine/Cm antibody
· STJ11103959 · DB/ELISA · Species independent Cm is a ribose 2'-O-methylation mark on RNA cytidine, distinct from the base methylation seen in 5mC and m5C. Validated by dot blot against modified and unmodified cytidine sequences. View product → |
Need help choosing an antibody?
Contact our technical support team for help selecting a rabbit polyclonal antibody for your target of interest. Each product page includes a downloadable datasheet and SDS, with dispatch on overnight priority shipping with gel ice packs.
Looking for more polyclonal antibodies?Explore our full range of polyclonal antibodies across goat, rabbit, chicken, and guinea pig hosts. |
View all polyclonal antibodies |
For Research Use Only. Not for use in diagnostic procedures.