Adenylate cyclase 1 Blocking Peptide peptide (STJ504512)
SPECIFICATIONS
ImmunogenSynthetic peptide taken within amino acid region 1030-1060 on rat/mouse Adenylyl Cyclase 1 protein.
General Information
| Short Description | Adenylate cyclase 1 Blocking Peptide is synthetically produced from the 1030-1060 sequence and is suitable for use in western blot applications. |
| Applications | Immunodepletion/Immunocompetition |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Formulation | Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice. |
| Storage Instruction | Store at-20ยฐC for long term storage. Avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | Adcy1 |
| Gene ID | 432530 |
| Uniprot ID | ADCY1_MOUSE |
| Immunogen | Synthetic peptide taken within amino acid region 1030-1060 on rat/mouse Adenylyl Cyclase 1 protein. |
| Immunogen Region | 1030-1060 |
Additional Info
| Tissue Specificity | Expressed throughout inner ear development. |
| Post Translational Modifications | N-glycosylated. |
| Function | Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. Mediates responses to increased cellular Ca(2+)/calmodulin levels. May be involved in regulatory processes in the central nervous system. May play a role in memory and learning. Plays a role in the regulation of the circadian rhythm of daytime contrast sensitivity probably by modulating the rhythmic synthesis of cyclic AMP in the retina. |
| Peptide Name | Adenylate Cyclase Type 1Atp Pyrophosphate-Lyase 1Adenylate Cyclase Type IAdenylyl Cyclase 1Ca(2+/Calmodulin-Activated Adenylyl Cyclase |
| Database Links | Reactome: R-MMU-163615Reactome: -MMU-170660Reactome: -MMU-170670Reactome: -MMU-418597Reactome: -MMU-5610787 |
| Cellular Localisation | MembraneMulti-Pass Membrane ProteinCell MembraneCytoplasmMembrane RaftExpressed In The Cytoplasm Of Supporting Cells And Hair Cells Of The Cochlea VestibuleAs Well As To The Cochlear Hair Cell Nuclei And Stereocilia| |
| Alternative Peptide Names | Adenylate Cyclase Type 1 proteinAtp Pyrophosphate-Lyase 1 proteinAdenylate Cyclase Type I proteinAdenylyl Cyclase 1 proteinCa(2+/Calmodulin-Activated Adenylyl Cyclase proteinAdcy1 protein |
Information sourced from Uniprot.org