ADCY3 Positive Control for STJ502067 peptide (STJ504554)

SKU:
STJ504554-5

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Applications: WB
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: ADCY3 Positive Control for STJ502067 is synthetically produced from the sequence and is suitable for use in western blot applications.
Formulation: Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is
Dilution Range: WB: 1:500
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: ADCY3
Gene ID: 109
Uniprot ID: ADCY3_HUMAN
Specificity: This is positive control is recommended for use in combination with ADCY3 antibody STJ502067.
Tissue Specificity Detected in zona glomerulosa and zona fasciculata in the adrenal gland (at protein level). Expressed in brain, heart, kidney, liver, lung, pancreas islets, placenta, and skeletal muscle. Detected in testis.
Post Translational Modifications Sumoylated. Sumoylation is required for targeting ot olfactory cilia. N-glycosylated. Rapidly phosphorylated after stimulation by odorants or forskolin. Phosphorylation by CaMK2 at Ser-1076 down-regulates enzyme activity.
Function Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. Participates in signaling cascades triggered by odorant receptors via its function in cAMP biosynthesis. Required for the perception of odorants. Required for normal sperm motility and normal male fertility. Plays a role in regulating insulin levels and body fat accumulation in response to a high fat diet.
Peptide Name Adenylate Cyclase Type 3
Atp Pyrophosphate-Lyase 3
Adenylate Cyclase Type Iii
Ac-Iii
Adenylate Cyclase - Olfactive Type
Adenylyl Cyclase 3
Ac3
Database Links Reactome: R-HSA-163359
Reactome: R-HSA-163615
Reactome: R-HSA-164378
Reactome: R-HSA-170660
Reactome: R-HSA-170670
Reactome: R-HSA-381753
Reactome: R-HSA-418555
Reactome: R-HSA-418594
Reactome: R-HSA-418597
Reactome: R-HSA-432040
Reactome: R-HSA-5610787
Reactome: R-HSA-9634597
Reactome: R-HSA-9660821
Reactome: R-HSA-9664323
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Cytoplasm
Cell Projection
Cilium
Golgi Apparatus
Also Detected In The Cytoplasm
Close To Lipid Droplets
Alternative Peptide Names Adenylate Cyclase Type 3 protein
Atp Pyrophosphate-Lyase 3 protein
Adenylate Cyclase Type Iii protein
Ac-Iii protein
Adenylate Cyclase - Olfactive Type protein
Adenylyl Cyclase 3 protein
Ac3 protein
ADCY3 protein
KIAA0511 protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance