ADCY3 Blocking Peptide for STJ502066 peptide (STJ504514)

Name: ADCY3 Blocking Peptide for STJ502066 peptide (STJ504514)
SKU: STJ504514-250
Price: 260.5 GBP
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ImmunogenSynthetic peptide corresponding to unique amino acid sequence on human Particulate Adenylyl Cyclase 3 protein.

STJ504514-250

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General Information

Short Description	ADCY3 Blocking Peptide for STJ502066 is synthetically produced from the sequence and is suitable for use in western blot applications.
Applications	Immunodepletion/Immunocompetition
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

Formulation	Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice.
Storage Instruction	Store at-20°C for long term storage. Avoid freeze-thaw cycles.

Target Information

Gene Symbol	ADCY3
Gene ID	109
Uniprot ID	ADCY3_HUMAN
Immunogen	Synthetic peptide corresponding to unique amino acid sequence on human Particulate Adenylyl Cyclase 3 protein.
Specificity	This blocking peptide is recommended for use in combination with ADCY3 antibody, STJ502066

Additional Info

Tissue Specificity	Detected in zona glomerulosa and zona fasciculata in the adrenal gland (at protein level). Expressed in brain, heart, kidney, liver, lung, pancreas islets, placenta, and skeletal muscle. Detected in testis.
Post Translational Modifications	Sumoylated. Sumoylation is required for targeting ot olfactory cilia. N-glycosylated. Rapidly phosphorylated after stimulation by odorants or forskolin. Phosphorylation by CaMK2 at Ser-1076 down-regulates enzyme activity.
Function	Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. Participates in signaling cascades triggered by odorant receptors via its function in cAMP biosynthesis: specifically activated by G alpha protein GNAL/G(olf) in olfactory epithelium. Required for normal sperm motility and normal male fertility. Plays a role in regulating insulin levels and body fat accumulation in response to a high fat diet.
Peptide Name	Adenylate Cyclase Type 3 Atp Pyrophosphate-Lyase 3 Adenylate Cyclase Type Iii Ac-Iii Adenylate Cyclase - Olfactive Type Adenylyl Cyclase 3 Ac3
Database Links	Reactome: R-HSA-163359 Reactome: R-HSA-163615 Reactome: R-HSA-164378 Reactome: R-HSA-170660 Reactome: R-HSA-170670 Reactome: R-HSA-381753 Reactome: R-HSA-418555 Reactome: R-HSA-418594 Reactome: R-HSA-418597 Reactome: R-HSA-432040 Reactome: R-HSA-5610787 Reactome: R-HSA-9634597 Reactome: R-HSA-9660821 Reactome: R-HSA-9664323
Cellular Localisation	Cell Membrane Multi-Pass Membrane Protein Cytoplasm Cell Projection Cilium Golgi Apparatus Also Detected In The Cytoplasm Close To Lipid Droplets
Alternative Peptide Names	Adenylate Cyclase Type 3 protein Atp Pyrophosphate-Lyase 3 protein Adenylate Cyclase Type Iii protein Ac-Iii protein Adenylate Cyclase - Olfactive Type protein Adenylyl Cyclase 3 protein Ac3 protein ADCY3 protein KIAA0511 protein

Information sourced from Uniprot.org

Citations

View product citations for antibody STJ504514-250 on CiteAb