Skn1 Positive Control for STJ506334 peptide (STJ506338)

SKU:
STJ506338-5

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Applications: WB
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Skn1 Positive Control for STJ506334 is synthetically produced from the 150-200 sequence and is suitable for use in western blot applications.
Formulation: Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: POU2F3
Gene ID: 25833
Uniprot ID: PO2F3_HUMAN
Immunogen Region: 150-200
Specificity: This is positive control is recommended for use in combination with Skn1 antibody STJ506334.
Tissue Specificity Specifically expressed in epidermis and cultured keratinocytes.
Function Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') and regulates cell type-specific differentiation pathways. Involved in the regulation of keratinocytes differentiation. The POU2F3-POU2AF2/POU2AF3 complex drives the expression of tuft-cell-specific genes, a rare chemosensory cells that coordinate immune and neural functions within mucosal epithelial tissues.
Peptide Name Pou Domain - Class 2 - Transcription Factor 3
Octamer-Binding Protein 11
Oct-11
Octamer-Binding Transcription Factor 11
Otf-11
Transcription Factor Pla-1
Transcription Factor Skn-1
Cellular Localisation Nucleus
Alternative Peptide Names Pou Domain - Class 2 - Transcription Factor 3 protein
Octamer-Binding Protein 11 protein
Oct-11 protein
Octamer-Binding Transcription Factor 11 protein
Otf-11 protein
Transcription Factor Pla-1 protein
Transcription Factor Skn-1 protein
POU2F3 protein
OTF11 protein
PLA1 protein

Information sourced from Uniprot.org

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