| Applications: |
WB |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Skn1 Positive Control for STJ506334 is synthetically produced from the 150-200 sequence and is suitable for use in western blot applications. |
| Formulation: |
Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is |
| Storage Instruction: |
Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: |
POU2F3 |
| Gene ID: |
25833 |
| Uniprot ID: |
PO2F3_HUMAN |
| Immunogen Region: |
150-200 |
| Specificity: |
This is positive control is recommended for use in combination with Skn1 antibody STJ506334. |
| Tissue Specificity | Specifically expressed in epidermis and cultured keratinocytes. |
| Function | Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') and regulates cell type-specific differentiation pathways. Involved in the regulation of keratinocytes differentiation. The POU2F3-POU2AF2/POU2AF3 complex drives the expression of tuft-cell-specific genes, a rare chemosensory cells that coordinate immune and neural functions within mucosal epithelial tissues. |
| Peptide Name | Pou Domain - Class 2 - Transcription Factor 3Octamer-Binding Protein 11Oct-11Octamer-Binding Transcription Factor 11Otf-11Transcription Factor Pla-1Transcription Factor Skn-1 |
| Cellular Localisation | Nucleus |
| Alternative Peptide Names | Pou Domain - Class 2 - Transcription Factor 3 proteinOctamer-Binding Protein 11 proteinOct-11 proteinOctamer-Binding Transcription Factor 11 proteinOtf-11 proteinTranscription Factor Pla-1 proteinTranscription Factor Skn-1 proteinPOU2F3 proteinOTF11 proteinPLA1 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
