Skn1 Blocking Peptide for STJ506334 peptide (STJ506337)
SPECIFICATIONS
General Information
| Short Description | Skn1 Blocking Peptide for STJ506334 is synthetically produced from the 150-200 sequence and is suitable for use in western blot applications. |
| Applications | Immunodepletion/Immunocompetition |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Formulation | Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice. |
| Storage Instruction | Store at-20ยฐC for long term storage. Avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | POU2F3 |
| Gene ID | 25833 |
| Uniprot ID | PO2F3_HUMAN |
| Immunogen Region | 150-200 |
| Specificity | This blocking peptide is recommended for use in combination with Skn1 antibody, STJ506334 |
Additional Info
| Tissue Specificity | Specifically expressed in epidermis and cultured keratinocytes. |
| Function | Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') and regulates cell type-specific differentiation pathways. Involved in the regulation of keratinocytes differentiation. The POU2F3-POU2AF2/POU2AF3 complex drives the expression of tuft-cell-specific genes, a rare chemosensory cells that coordinate immune and neural functions within mucosal epithelial tissues. |
| Peptide Name | Pou Domain - Class 2 - Transcription Factor 3Octamer-Binding Protein 11Oct-11Octamer-Binding Transcription Factor 11Otf-11Transcription Factor Pla-1Transcription Factor Skn-1 |
| Cellular Localisation | Nucleus |
| Alternative Peptide Names | Pou Domain - Class 2 - Transcription Factor 3 proteinOctamer-Binding Protein 11 proteinOct-11 proteinOctamer-Binding Transcription Factor 11 proteinOtf-11 proteinTranscription Factor Pla-1 proteinTranscription Factor Skn-1 proteinPOU2F3 proteinOTF11 proteinPLA1 protein |
Information sourced from Uniprot.org