• Rat MMP-9 protein (Recombinant) (C-His) (STJP001226)
  • Rat MMP-9 protein (Recombinant) (C-His) (STJP001226)
  • Rat MMP-9 protein (Recombinant) (C-His) (STJP001226)
  • Rat MMP-9 protein (Recombinant) (C-His) (STJP001226)

Rat MMP-9 protein (Recombinant) (C-His) (STJP001226)

SKU:
STJP001226

£316.50 - £493.50
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Host: HEK293 cells
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Formulation: Lyophilised from a 0.22 Mu m filtered solution of 50mM Tris, 10mM CaCl2, 150mM NaCl, pH 7.5.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Determination Method: < 0.1 EU/Mu g of the protein by LAL method.
Immunoreactivity: 1.Measured in a cell migration assay using Hela cells. 1 ng/mL of Recombinant Rat MMP-9 can effectively induce Hela cells migration.|2.Measured by its ability to cleave the fluorogenic peptide substrate Mca-PLGL-Dpa-AR-NH2. The specific activity is >
Gene Symbol: Mmp9
Gene ID: 81687
Uniprot ID: MMP9_RAT
Immunogen Region: Leu35-Pro708
Immunogen: Recombinant Rat MMP-9 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Leu35-Pro708) of rat MMP-9 (Accession #NP_038627.1.) fused with a 6×His tag at the C-terminus.
Immunogen Sequence: LKTSNLTDTQLAEDYLYRYG YTRAAQMMGEKQSLRPALLM LQKQLSLPQTGELDSETLKA IRSPRCGVPDVGKFQTFEGD LKWHHHNITYWIQSYTEDLP RDVIDDSFARAFAVWSAVTP LTFTRVYGLEADIVIQFGVA EHGDGYPFDGKDGLLAHAFP PGPGIQGDAHFDDDELWSLG KGAVVPTYFGNANGAPCHFP FTFEGRSYLSCTTDGRNDGK PWCGTTADYDTDRKYGFCP
Post Translational Modifications N- and O-glycosylated.
Function Matrix metalloproteinase that plays an essential role in local proteolysis of the extracellular matrix and in leukocyte migration. Could play a role in bone osteoclastic resorption. Cleaves KiSS1 at a Gly-|-Leu bond. Cleaves NINJ1 to generate the Secreted ninjurin-1 form. Cleaves type IV and type V collagen into large C-terminal three quarter fragments and shorter N-terminal one quarter fragments. Degrades fibronectin but not laminin or Pz-peptide.
Protein Name Matrix Metalloproteinase-9
Mmp-9
92 Kda Gelatinase
92 Kda Type Iv Collagenase
Gelatinase B
Gelb
Database Links Reactome: R-RNO-1433557
Reactome: -RNO-1442490
Reactome: -RNO-1474228
Reactome: -RNO-1592389
Reactome: -RNO-2022090
Reactome: -RNO-3928665
Reactome: -RNO-6798695
Reactome: -RNO-9009391
Cellular Localisation Secreted
Extracellular Space
Extracellular Matrix
Alternative Protein Names Matrix Metalloproteinase-9 protein
Mmp-9 protein
92 Kda Gelatinase protein
92 Kda Type Iv Collagenase protein
Gelatinase B protein
Gelb protein
Mmp9 protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance