This Il1r1 Sandwich ELISA is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in rat serum, plasma and other biological fluids.
Applications
ELISA
Reactivity
Rat
Sensitivity
46.88pg/mL
Detection Limit
78.13~5000pg/mL
Note
FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS.
Product Properties
Storage Instruction
If unopened the kit may be stored at 2-8°C for up to 1 month. If the kit will not be used within 1 month, store the components separately, according to the component table in the manual.
This kit recognizes Rat IL-1R1 in samples. No significant cross-reactivity or interference between Rat IL-1R1 and analogues was observed.
Sample Type
Serum, plasma and other biological fluids
Additional Info
Function
Receptor for IL1A, IL1B and IL1RN. After binding to interleukin-1 associates with the coreceptor IL1RAP to form the high affinity interleukin-1 receptor complex which mediates interleukin-1-dependent activation of NF-kappa-B, MAPK and other pathways. Signaling involves the recruitment of adapter molecules such as TOLLIP, MYD88, and IRAK1 or IRAK2 via the respective TIR domains of the receptor/coreceptor subunits. Binds ligands with comparable affinity and binding of antagonist IL1RN prevents association with IL1RAP to form a signaling complex. Involved in IL1B-mediated costimulation of IFNG production from T-helper 1 (Th1) cells.
Protein Name
Interleukin-1 Receptor Type 1Il-1r-1Il-1rt-1Il-1rt1Cd121 Antigen-Like Family Member AInterleukin-1 Receptor AlphaIl-1r-AlphaInterleukin-1 Receptor Type IP80Cd Antigen Cd121a Cleaved Into - Interleukin-1 Receptor Type 1 - Membrane FormMil-1r1Mil-1ri - Interleukin-1 Receptor Type 1 - Soluble FormSil-1r1Sil-1ri
Cellular Localisation
MembraneSingle-Pass Type I Membrane ProteinCell MembraneSecreted
Alternative ELISA Names
Interleukin-1 Receptor Type 1 ELISA kitIl-1r-1 ELISA kitIl-1rt-1 ELISA kitIl-1rt1 ELISA kitCd121 Antigen-Like Family Member A ELISA kitInterleukin-1 Receptor Alpha ELISA kitIl-1r-Alpha ELISA kitInterleukin-1 Receptor Type I ELISA kitP80 ELISA kitCd Antigen Cd121a Cleaved Into - Interleukin-1 Receptor Type 1 - Membrane Form ELISA kitMil-1r1 ELISA kitMil-1ri - Interleukin-1 Receptor Type 1 - Soluble Form ELISA kitSil-1r1 ELISA kitSil-1ri ELISA kitIl1r1 ELISA kitIl1ra ELISA kit
Specificity
This kit recognizes Rat IL-1R1 in samples. No significant cross-reactivity or interference between Rat IL-1R1 and analogues was observed.
