| Host: | Mouse/Goat |
| Applications: | ELISA |
| Reactivity: | Rat |
| Note: | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
| Short Description : | This ICAM-1/CD54 antibody pair contains complimentary capture and detection antibodies, which work together under the principals of the Sandwich ELISA. |
| Clonality : | Monoclonal/Polyclonal |
| Conjugation: | Unconjugated/Biotin |
| Formulation: | Capture Buffer: PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4.Detection Buffer: PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4. |
| Purification: | Capture Purification: Protein A or G.Detection Purification: Antigen Affinity. |
| Concentration: | 0.5 mg/mL |
| Storage Instruction: | Store at-20°C for long term, and avoid freeze-thaw cycles. |
| Gene Symbol: | Icam1 |
| Gene ID: | 25464 |
| Uniprot ID: | ICAM1_RAT |
| Immunogen: | Capture immunogen: Recombinant Rat ICAM-1/CD54 protein.Detection Immunogen: Recombinant Rat ICAM-1/CD54 protein. |
| Function | ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation. |
| Protein Name | Intercellular Adhesion Molecule 1Icam-1Cd Antigen Cd54 |
| Database Links | Reactome: R-RNO-198933Reactome: -RNO-216083 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Pair Names | Intercellular Adhesion Molecule 1 antibody pairIcam-1 antibody pairCd Antigen Cd54 antibody pairIcam1 antibody pairIcam-1 antibody pair |
Information sourced from Uniprot.org