Rat FAS/CD95 (Tumor Necrosis Factor Receptor Superfamily Member 6) Antibody Pair (STJAP00351)

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STJAP00351-50
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Host: Goat/Goat
Applications: ELISA
Reactivity: Rat
Note: FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS.
Short Description : This FAS/CD95 antibody pair contains complimentary capture and detection antibodies, which work together under the principals of the Sandwich ELISA.
Clonality : Polyclonal/Polyclonal
Conjugation: Unconjugated/Biotin
Formulation: Capture Buffer: PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4.
Detection Buffer: PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4.
Purification: Capture Purification: Antigen Affinity.
Detection Purification: Antigen Affinity.
Concentration: 0.5 mg/mL
Storage Instruction: Store at-20°C for long term, and avoid freeze-thaw cycles.
Gene Symbol: Fas
Gene ID: 246097
Uniprot ID: TNR6_RAT
Immunogen: Capture immunogen: Recombinant Rat FAS/CD95 protein.
Detection Immunogen: Recombinant Rat FAS/CD95 protein.
Function Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase CASP8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs CASP8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both.
Protein Name Tumor Necrosis Factor Receptor Superfamily Member 6
Apo-1 Antigen
Apoptosis-Mediating Surface Antigen Fas
Faslg Receptor
Cd Antigen Cd95
Database Links Reactome: R-RNO-3371378
Reactome: -RNO-5218900
Reactome: -RNO-69416
Reactome: -RNO-75157
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Membrane Raft
Alternative Antibody Pair Names Tumor Necrosis Factor Receptor Superfamily Member 6 antibody pair
Apo-1 Antigen antibody pair
Apoptosis-Mediating Surface Antigen Fas antibody pair
Faslg Receptor antibody pair
Cd Antigen Cd95 antibody pair
Fas antibody pair
Apt1 antibody pair
Tnfrsf6 antibody pair

Information sourced from Uniprot.org

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