Rat CD38 protein (Recombinant) (STJP000634)

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STJP000634
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Short Description :Recombinant-Rat CD38-protein was developed from hek293. For use in research applications.
Host:HEK293
Note:STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Conjugation:Unconjugated
Formulation:0.2 Mu m filtered PBS solution, pH7.2.
Storage Instruction:Can be stored in working aliquots at 2°C-8°C C for one month, or at-20°C to-70°C for 1 year. Avoid repeated freeze/thaw cycles. NA
Endotoxin:Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg (1EU/µg). NA
Gene Symbol:Cd38
Gene ID:25668
Uniprot ID:CD38_RAT
Immunogen:Optimized DNA sequence encoding extracellular domain of Rat CD38 including a C-terminal 6His tag was expressed in HEK293 cells. NA
Immunogen Region:ECD
Tissue Specificity Spleen, liver, heart, thymus, thyroid gland, ileum, colon, cerebellum, salivary gland, adrenal gland, jejunum, islets of Langerhans and osteoclasts.
Function Synthesizes the second messengers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger for glucose-induced insulin secretion, the latter a Ca(2+) mobilizer. Also has cADPR hydrolase activity. Regulates osteoclastic bone resorption, probably via production of cyclic ADP-ribose and triggering of a cytosolic calcium ion signal through ryanodine receptor activation.
Protein Name Adp-Ribosyl Cyclase/Cyclic Adp-Ribose Hydrolase 1
2'-Phospho-Adp-Ribosyl Cyclase
2'-Phospho-Adp-Ribosyl Cyclase/2'-Phospho-Cyclic-Adp-Ribose Transferase
2'-Phospho-Cyclic-Adp-Ribose Transferase
Adp-Ribosyl Cyclase 1
Adprc 1
Cd38h
Cyclic Adp-Ribose Hydrolase 1
Cadpr Hydrolase 1
Cd Antigen Cd38
Database Links Reactome: R-RNO-196807
Cellular Localisation Cell Membrane
Single-Pass Type Ii Membrane Protein
Alternative Protein Names Adp-Ribosyl Cyclase/Cyclic Adp-Ribose Hydrolase 1 protein
2'-Phospho-Adp-Ribosyl Cyclase protein
2'-Phospho-Adp-Ribosyl Cyclase/2'-Phospho-Cyclic-Adp-Ribose Transferase protein
2'-Phospho-Cyclic-Adp-Ribose Transferase protein
Adp-Ribosyl Cyclase 1 protein
Adprc 1 protein
Cd38h protein
Cyclic Adp-Ribose Hydrolase 1 protein
Cadpr Hydrolase 1 protein
Cd Antigen Cd38 protein
Cd38 protein

Information sourced from Uniprot.org

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