Monoclonal Antibodies

Primary Antibodies

Monoclonal Antibodies

Monoclonal antibodies are produced in laboratories to enhance, restore or mimic the immune system's attack on cancer cells. They are made by cloning a specific white blood cell, so every monoclonal antibody can be traced back to a single parent cell.

Browse all monoclonal antibodies
About monoclonal antibodies How they're made Featured hosts
Product overview

What are monoclonal antibodies?

St John's Laboratory lists tens of thousands of monoclonal antibodies, all traceable to a single parent cell line.

  • A single, consistent epitope Because every monoclonal antibody descends from one parent cell, it binds the same epitope every time, giving consistent results across repeat experiments.
  • Can be designed for monovalent affinity Monoclonal antibodies can also be engineered to have monovalent affinity for their target.
  • A wide range of host species St John's Laboratory offers 39,843 monoclonal antibodies across a range of host species, including mouse, rabbit, and cell-line-derived hosts such as 293F and CHO cells.
Production process

How monoclonal antibodies are made

When an antigen is introduced to either a mouse or a rabbit and polyclonal B cells are fused from the spleen to the myeloma, a hybridoma is created. That hybridoma is then cultured to continue antibody production.

Featured hosts

Featured hosts

Monoclonal antibodies on this page are raised in a range of host species, including the following.

293F Cells (654) Armenian Hamster (251) Chicken (174) CHO Cells (52) Canine (19) Alpaca (10)

Need help choosing an antibody?

Contact our technical support team for help selecting an antibody for your target of interest. Each product page includes a downloadable datasheet and SDS, with dispatch on overnight priority shipping with gel ice packs.

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