| Applications: |
WB |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
PP1R3A Positive Control for STJ506061 is synthetically produced from the sequence and is suitable for use in western blot applications. |
| Formulation: |
Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is |
| Storage Instruction: |
Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: |
PPP1R3A |
| Gene ID: |
5506 |
| Uniprot ID: |
PPR3A_HUMAN |
| Specificity: |
This is positive control is recommended for use in combination with PP1R3A antibody STJ506061. |
| Immunogen: |
Purified protein. |
| Tissue Specificity | Skeletal muscle and heart. |
| Post Translational Modifications | Phosphorylation at Ser-46 by ISPK stimulates the dephosphorylation of glycogen synthase and phosphorylase kinase. |
| Function | Seems to act as a glycogen-targeting subunit for PP1. PP1 is essential for cell division, and participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Plays an important role in glycogen synthesis but is not essential for insulin activation of glycogen synthase. |
| Peptide Name | Protein Phosphatase 1 Regulatory Subunit 3aProtein Phosphatase 1 Glycogen-Associated Regulatory SubunitProtein Phosphatase Type-1 Glycogen Targeting SubunitRg1 |
| Cellular Localisation | MembraneSingle-Pass Membrane Protein |
| Alternative Peptide Names | Protein Phosphatase 1 Regulatory Subunit 3a proteinProtein Phosphatase 1 Glycogen-Associated Regulatory Subunit proteinProtein Phosphatase Type-1 Glycogen Targeting Subunit proteinRg1 proteinPPP1R3A proteinPP1G protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
