| Applications: | WB |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Phospho-PGCA Positive Control is synthetically produced from the sequence and is suitable for use in western blot applications. |
| Dilution Range: | WB: 1:500 |
| Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: | NPR1 |
| Gene ID: | 4881 |
| Uniprot ID: | ANPRA_HUMAN |
| Post Translational Modifications | Phosphorylation of the protein kinase-like domain is required for full activation by ANP. |
| Function | Receptor for the atrial natriuretic peptide NPPA/ANP and the brain natriuretic peptide NPPB/BNP which are potent vasoactive hormones playing a key role in cardiovascular homeostasis. Has guanylate cyclase activity upon binding of the ligand. |
| Peptide Name | Atrial Natriuretic Peptide Receptor 1 Atrial Natriuretic Peptide Receptor Type A Anp-A Anpr-A Npr-A Guanylate Cyclase A Gc-A |
| Database Links | Reactome: R-HSA-5578768 |
| Cellular Localisation | Membrane Single-Pass Type I Membrane Protein |
| Alternative Peptide Names | Atrial Natriuretic Peptide Receptor 1 protein Atrial Natriuretic Peptide Receptor Type A protein Anp-A protein Anpr-A protein Npr-A protein Guanylate Cyclase A protein Gc-A protein NPR1 protein ANPRA protein |
Information sourced from Uniprot.org