Post Translational Modifications | N-glycosylated. N-linked glycosylation on Asn-35 and Asn-175 is critical for secretion but not for preadipocyte cell differentiation activity. |
Function | Plays a role in the regulation of the early stage of white and brown preadipocyte cell differentiation. Promotes adipogenic commitment of preadipocytes by increasing gene expression of the transcription factor PPARG in a BMP4-dependent signaling pathway. |
Protein Name | V-Set And Transmembrane Domain-Containing Protein 2a |
Cellular Localisation | SecretedSecreted By Adipose Precursor CellsNot Detected In The Nucleus |
Alternative Protein Names | V-Set And Transmembrane Domain-Containing Protein 2a proteinVstm2a proteinVstm2 protein |
Information sourced from Uniprot.org