Tissue Specificity | Expressed in the sciatic nerve (at protein level). |
Post Translational Modifications | O-glycosylated. Phosphorylated in the head and rod regions by the PKC kinase PKN1, leading to the inhibition of polymerization. Ubiquitinated in the presence of TRIM2 and UBE2D1. |
Function | Neurofilaments usually contain three intermediate filament proteins: NEFL, NEFM, and NEFH which are involved in the maintenance of neuronal caliber. May additionally cooperate with the neuronal intermediate filament proteins PRPH and INA to form neuronal filamentous networks. |
Protein Name | Neurofilament Light PolypeptideNf-L68 Kda Neurofilament ProteinNeurofilament Triplet L Protein |
Database Links | Reactome: R-MMU-438066Reactome: -MMU-5673001 |
Cellular Localisation | Cell ProjectionAxonCytoplasmCytoskeleton |
Alternative ELISA Names | Neurofilament Light Polypeptide ELISA kitNf-L ELISA kit68 Kda Neurofilament Protein ELISA kitNeurofilament Triplet L Protein ELISA kitNefl ELISA kitNf68 ELISA kitNfl ELISA kit |
output | |
Information sourced from Uniprot.org