Mouse Macrophage migration inhibitory factor/MIF protein (Recombinant) (N-hFC) (STJP002982)

SKU:
STJP002982

$131.63 - $393.53
Current Stock:
Host: HEK293 cells
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Formulation: Lyophilised from a 0.22 Mu m filtered solution of 50mM Tris 150mM NaCl pH 8.0.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Determination Method: < 0.1 EU/Mu g
Gene Symbol: Mif
Gene ID: 17319
Uniprot ID: MIF_MOUSE
Immunogen Region: Pro2-Ala115
Immunogen: Recombinant Mouse Macrophage migration inhibitory factor/MIF Protein is produced by E. coli expression system. The target protein is expressed with sequence (Pro2-Ala115) of mouse Macrophage migration inhibitory factor/MIF (Accession #NP_03492
Immunogen Sequence: IWSAVFLNSLFNQEVQIPLT ESYCGPCPKNWICYKNNCYQ FFDESKNWYESQASCMSQNA SLLKVYSKEDQDLLKLVKSY HWMGLVHIPTNGSWQWEDGS ILSPNLLTIIEMQKGDCALY ASSFKGYIENCSTPNTYICM QRTV
Function Pro-inflammatory cytokine involved in the innate immune response to bacterial pathogens. The expression of MIF at sites of inflammation suggests a role as mediator in regulating the function of macrophages in host defense. Counteracts the anti-inflammatory activity of glucocorticoids. Has phenylpyruvate tautomerase and dopachrome tautomerase activity (in vitro), but the physiological substrate is not known. It is not clear whether the tautomerase activity has any physiological relevance, and whether it is important for cytokine activity.
Protein Name Macrophage Migration Inhibitory Factor
Mif
Delayed Early Response Protein 6
Der6
Glycosylation-Inhibiting Factor
Gif
L-Dopachrome Isomerase
L-Dopachrome Tautomerase
Phenylpyruvate Tautomerase
Database Links Reactome: R-MMU-202733
Reactome: -MMU-6798695
Cellular Localisation Secreted
Cytoplasm
Does Not Have A Cleavable Signal Sequence And Is Secreted Via A Specialized
Non-Classical Pathway
Secreted By Macrophages Upon Stimulation By Bacterial Lipopolysaccharide (Lps)
Or By M
Tuberculosis Antigens
Alternative Protein Names Macrophage Migration Inhibitory Factor protein
Mif protein
Delayed Early Response Protein 6 protein
Der6 protein
Glycosylation-Inhibiting Factor protein
Gif protein
L-Dopachrome Isomerase protein
L-Dopachrome Tautomerase protein
Phenylpyruvate Tautomerase protein
Mif protein

Information sourced from Uniprot.org

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