Mouse L-Selectin (CD62L) protein (Recombinant) (STJP000462)

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STJP000462
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Host: HEK293
Note: STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Mouse L-Selectin (CD62L)-protein was developed from hek293. For use in research applications.
Conjugation: Unconjugated
Formulation: Lyophilised from 0.2 Mu m filtered PBS solution, pH7.2, 5% Trehalose.
Storage Instruction: Can be stored in working aliquots at 2°C-8°C C for one month, or at-20°C to-70°C for 1 year. Avoid repeated freeze/thaw cycles. NA
Endotoxin: Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg (1EU/µg). NA
Immunoreactivity: The activity was tested by the ability of immobilized recombinant Mouse L-Selectin to bind Human U937 lymphoma cells NA
Gene Symbol: Sell
Gene ID: 20343
Uniprot ID: LYAM1_MOUSE
Immunogen Region: ECD
Immunogen: Optimized DNA sequence encoding extracellular domain of Mouse L-Selectin including a C-terminal IgG1 Fc tag was expressed in HEK293 cells. NA
Tissue Specificity Predominantly expressed in lymphoid tissue.
Post Translational Modifications N-glycosylated.
Function Calcium-dependent lectin that mediates cell adhesion by binding to glycoproteins on neighboring cells. Mediates the adherence of lymphocytes to endothelial cells of high endothelial venules in peripheral lymph nodes. Promotes initial tethering and rolling of leukocytes in endothelia.
Protein Name L-Selectin
Cd62 Antigen-Like Family Member L
Leukocyte Adhesion Molecule 1
Lam-1
Leukocyte-Endothelial Cell Adhesion Molecule 1
Lecam1
Lymph Node Homing Receptor
Lymphocyte Antigen 22
Ly-22
Lymphocyte Surface Mel-14 Antigen
Cd Antigen Cd62l
Database Links Reactome: R-MMU-198933
Reactome: -MMU-202733
Reactome: -MMU-6798695
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Protein Names L-Selectin protein
Cd62 Antigen-Like Family Member L protein
Leukocyte Adhesion Molecule 1 protein
Lam-1 protein
Leukocyte-Endothelial Cell Adhesion Molecule 1 protein
Lecam1 protein
Lymph Node Homing Receptor protein
Lymphocyte Antigen 22 protein
Ly-22 protein
Lymphocyte Surface Mel-14 Antigen protein
Cd Antigen Cd62l protein
Sell protein
Lnhr protein
Ly-22 protein
Ly22 protein

Information sourced from Uniprot.org

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