• Mouse IL-15RA/CD215 protein (Recombinant) (C-hFc&His) (STJP001365)
  • Mouse IL-15RA/CD215 protein (Recombinant) (C-hFc&His) (STJP001365)
  • Mouse IL-15RA/CD215 protein (Recombinant) (C-hFc&His) (STJP001365)
  • Mouse IL-15RA/CD215 protein (Recombinant) (C-hFc&His) (STJP001365)

Mouse IL-15RA/CD215 protein (Recombinant) (C-hFc&His) (STJP001365)

SKU:
STJP001365

£55.50 - £156.50
Current Stock:
Host: HEK293 cells
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Recombinant-Mouse IL-15RA/CD215-C-hFc&His protein was developed from hek293 cells and has a target region of C-hFc&His. For use in research applications.
Formulation: Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4.
Immunoreactivity: Measured by its binding ability in a functional ELISA. Immobilized Human IL15 at 1 Mu g/mL (100 Mu L/well) can bind Mouse IL15RA with a linear range of 0.3-77 ng/mL.
Gene Symbol: Il15ra
Gene ID: 16169
Uniprot ID: I15RA_MOUSE
Immunogen: Recombinant Mouse IL-15RA/CD215 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Gly33-Lys205) of mouse IL15RA/CD215 (Accession #NP_032384.1) fused with a Fc, 6×His tag at the C-terminus.
Post Translational Modifications N-glycosylated and O-glycosylated. A soluble form (sIL-15RA) arises from proteolytic shedding of the membrane-anchored receptor. It also binds IL15 and thus interferes with IL15 binding to the membrane receptor.
Function High-affinity receptor for interleukin-15. Can signal both in cis and trans where IL15R from one subset of cells presents IL15 to neighboring IL2RG-expressing cells. In neutrophils, binds and activates kinase SYK in response to IL15 stimulation. In neutrophils, required for IL15-induced phagocytosis in a SYK-dependent manner.
Protein Name Interleukin-15 Receptor Subunit Alpha
Il-15 Receptor Subunit Alpha
Il-15r-Alpha
Il-15ra
Cd Antigen Cd215 Cleaved Into - Soluble Interleukin-15 Receptor Subunit Alpha
Sil-15 Receptor Subunit Alpha
Sil-15r-Alpha
Sil-15ra
Database Links Reactome: R-MMU-8983432
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Nucleus Membrane
Cell Surface
Soluble Interleukin-15 Receptor Subunit Alpha: Secreted
Extracellular Space
Alternative Protein Names Interleukin-15 Receptor Subunit Alpha protein
Il-15 Receptor Subunit Alpha protein
Il-15r-Alpha protein
Il-15ra protein
Cd Antigen Cd215 Cleaved Into - Soluble Interleukin-15 Receptor Subunit Alpha protein
Sil-15 Receptor Subunit Alpha protein
Sil-15r-Alpha protein
Sil-15ra protein
Il15ra protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance