| Host: |
HEK293 cells |
| Reactivity: |
Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Recombinant-Mouse Erythropoietin/EPO-Avi & His Tag protein was developed from hek293 cells and has a target region of Avi & His Tag. For use in research applications. |
| Formulation: |
Lyophilized from a 0.22 Mu m filtered solution of 20 mM NaAc, pH 4.5 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Immunoreactivity: |
Recombinant Mouse EPO stimulates cell proliferation of the TF‑1 human erythroleukemic cells. The ED50 for this effect is 4.3-17.3 ng/mL.corresponding to a specific activity of 5.78×104-2.33×105units/mg. |
| Gene Symbol: |
Epo |
| Gene ID: |
13856 |
| Uniprot ID: |
EPO_MOUSE |
| Immunogen Region: |
Ala27-Arg192 |
| Immunogen: |
Recombinant Mouse Erythropoietin/EPO Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Ala27-Arg192) of mouse Erythropoietin/EPO (Accession #) fused with a 6×His tag and Avi at the C-terminus. |
| Function | Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. |
| Protein Name | Erythropoietin |
| Database Links | Reactome: R-MMU-9027276Reactome: -MMU-9027284 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Erythropoietin proteinEpo protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
