Mouse CD59 (Protectin) Sandwich ELISA Kit (STJE0007819)
SPECIFICATIONS
General Information
| Short Description | This CD59 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse serum, plasma, urine or other biological fluids.. |
| Applications | ELISA |
| Reactivity | Mouse |
| Sensitivity | 25.5pg/mL |
| Detection Limit | 62.5-4000pg/mL |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Storage Instruction | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time | 4.5 hrs |
Target Information
| Gene Symbol | Cd59a |
| Gene ID | 12509 |
| Uniprot ID | CD59A_MOUSE |
| Sample Type | serum, plasma, urine or other biological fluids. |
Additional Info
| Tissue Specificity | Expressed in all tissues examined (liver, kidney, spleen, thymus, brain and heart). Low levels in thymus. Also expressed in mononuclear cells, erythrocytes and platelets. Barely detected in neutrophils. |
| Post Translational Modifications | N- and O-glycosylated. |
| Function | Potent inhibitor of the complement membrane attack complex (MAC) action, which protects self-cells from damage during complement activation. Acts by binding to the beta-haipins of C8 (C8A and C8B) components of the assembling MAC, forming an intermolecular beta-sheet that prevents incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. |
| Protein Name | Cd59a GlycoproteinMac-Inhibitory ProteinMac-IpMembrane Attack Complex Inhibition FactorMacifProtectinCd Antigen Cd59 |
| Database Links | |
| Cellular Localisation | Cell MembraneLipid-AnchorGpi-AnchorSecretedLocalizes To The Cell SurfaceSoluble Form Found In A Number Of Tissues |
| Alternative ELISA Names | Cd59a Glycoprotein ELISA kitMac-Inhibitory Protein ELISA kitMac-Ip ELISA kitMembrane Attack Complex Inhibition Factor ELISA kitMacif ELISA kitProtectin ELISA kitCd Antigen Cd59 ELISA kitCd59a ELISA kitCd59 ELISA kit |
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Information sourced from Uniprot.org