| Host: |
HEK293 cells |
| Reactivity: |
Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Recombinant-Mouse CD276-C-hFc protein was developed from hek293 cells and has a target region of C-hFc. For use in research applications. |
| Formulation: |
Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Immunoreactivity: |
Measured by its binding ability in a functional ELISA.Immobilized Mouse CD276 (Catalog: RP01674) at 2 Mu g/mL (100 Mu L/well) can bind CD276 Rabbit polyclonal antibody (Catalog: A21663) with a linear range of 1-77.4 ng/mL. |
| Gene Symbol: |
Cd276 |
| Gene ID: |
102657 |
| Uniprot ID: |
CD276_MOUSE |
| Immunogen Region: |
Val 29-Phe 244 |
| Immunogen: |
Recombinant Mouse CD276 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Val 29-Phe 244) of mouse CD276 (Accession #NP_598744.1) fused with and a hFc tag at the C-terminus. |
| Function | Modulates T-cell-mediated immune responses and the development of acute and chronic transplant rejection. Plays a positive regulatory role in bone formation and has a dual role in the bone-immune interface. Induces antitumor immunity as it activates both acquired and innate immunity leading to natural killer cell and CD8 T-cell dependent killing of tumor cells. |
| Protein Name | Cd276 AntigenB7 Homolog 3B7-H3Costimulatory MoleculeCd Antigen Cd276 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Protein Names | Cd276 Antigen proteinB7 Homolog 3 proteinB7-H3 proteinCostimulatory Molecule proteinCd Antigen Cd276 proteinCd276 proteinB7h3 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
