Mouse B7-H2/ICOSLG/CD275 protein (Recombinant) (C-His) (STJP002774)

SKU:
STJP002774

£72.50 - £223.50
Current Stock:
Host: HEK293 cells
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Recombinant-Mouse B7-H2/ICOSLG/CD275-C-His protein was developed from hek293 cells and has a target region of C-His. For use in research applications.
Formulation: Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: Icoslg
Gene ID: 50723
Uniprot ID: ICOSL_MOUSE
Immunogen Region: Glu47-Lys279
Immunogen: Recombinant Mouse B7-H2/ICOSLG/CD275 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Glu47-Lys279) of mouse B7-H2/ICOSLG/CD275 (Accession #NP_056605.1) fused with a 6×His tag at the C-terminus.
Function Ligand for the T-cell-specific cell surface receptor ICOS. Acts as a costimulatory signal for T-cell proliferation and cytokine secretion.induces also B-cell proliferation and differentiation into plasma cells. Could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co-stimulating memory T-cell function. During pregnancy, may function to skew the cytokine of maternal T-cells toward immunoprotective Th2 phenotype.
Protein Name Icos Ligand
B7 Homolog 2
B7-H2
B7-Like Protein Gl50
B7-Related Protein 1
B7rp-1
Licos
Cd Antigen Cd275
Database Links Reactome: R-MMU-388841
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Protein Names Icos Ligand protein
B7 Homolog 2 protein
B7-H2 protein
B7-Like Protein Gl50 protein
B7-Related Protein 1 protein
B7rp-1 protein
Licos protein
Cd Antigen Cd275 protein
Icoslg protein
B7h2 protein
B7rp1 protein
Icosl protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance